Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADU47515.1Hypothetical protein; InterPro IPR000560: IPR006230; KEGG: stp:Strop_2268 hypothetical protein; SPTR: Glutamate mutase, mutL; TIGRFAM: conserved hypothetical protein. (450 aa)    
Predicted Functional Partners:
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
 
 0.971
ADU48035.1
Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein.
 
 
 0.912
ADU48304.1
InterPro IPR006158; KEGG: nca:Noca_2664 beta-lysine 5,6-aminomutase beta subunit / D-lysine 5,6-aminomutase beta subunit; PFAM: cobalamin B12-binding domain protein; SPTR: Beta-lysine 5,6-aminomutase beta subunit / D-lysine 5,6-aminomutase beta subunit; PFAM: B12 binding domain.
 
     0.808
ddl
D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
  
  
 0.806
ADU48302.1
KEGG: kfl:Kfla_3604 L-erythro-3,5-diaminohexanoate dehydrogenase; SPTR: Zn-dependent alcohol dehydrogenase and related dehydrogenase protein; PFAM: Zinc-binding dehydrogenase.
 
     0.794
ADU48305.1
InterPro IPR006683; KEGG: sna:Snas_3948 3-aminobutyryl-CoA ammonia-lyase; PFAM: thioesterase superfamily protein; SPTR: Putative uncharacterized protein; PFAM: Thioesterase superfamily.
 
     0.782
ADU48303.1
InterPro IPR015130; KEGG: kfl:Kfla_3602 D-lysine 56-aminomutase alpha subunit; PFAM: D-Lysine 56-aminomutase alpha subunit; SPTR: Lysine 5,6-aminomutase alpha subunit; PFAM: D-Lysine 5,6-aminomutase alpha subunit.
 
     0.781
sepF
Protein of unknown function DUF552; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
  
 
 0.698
ADU49438.1
3-keto-5-aminohexanoate cleavage enzyme; COGs: COG3246 conserved hypothetical protein; InterPro IPR008567; KEGG: kfl:Kfla_0987 protein of unknown function DUF849; PFAM: protein of unknown function DUF849; SPTR: Putative uncharacterized protein; PFAM: Prokaryotic protein of unknown function (DUF849).
 
     0.684
ADU47514.1
Cys/Met metabolism pyridoxal-phosphate-dependent protein; COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277; KEGG: nca:Noca_0976 cystathionine gamma-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; SPTR: Cystathionine gamma-synthase; PFAM: Cys/Met metabolism PLP-dependent enzyme.
       0.667
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
Server load: low (14%) [HD]