Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADU47538.1KEGG: krh:KRH_06700 hypothetical protein; SPTR: Putative uncharacterized protein. (412 aa)    
Predicted Functional Partners:
ADU47314.1
COGs: COG1010 Precorrin-3B methylase; InterPro IPR000878: IPR006364: IPR006363; KEGG: nda:Ndas_1624 precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; SPTR: Precorrin-3B C17-methyltransferase; TIGRFAM: precorrin-3B C17-methyltransferase; precorrin-2 C20-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-3B C17-methyltransferase; precorrin-2 C20-methyltransferase.
  
  
 0.916
ADU47339.1
COGs: COG2875 Precorrin-4 methylase; InterPro IPR000878: IPR003043; KEGG: tfu:Tfu_0315 precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; SPTR: Putative methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-4 C11-methyltransferase; Belongs to the precorrin methyltransferase family.
  
  
 0.717
ADU49439.1
Folate-binding protein YgfZ; COGs: COG0354 aminomethyltransferase related to GcvT; InterPro IPR006222: IPR013977: IPR017703; KEGG: kse:Ksed_03590 folate-binding protein YgfZ; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; SPTR: Putative uncharacterized protein; TIGRFAM: folate-binding protein YgfZ; PFAM: Glycine cleavage T-protein C-terminal barrel domain; Aminomethyltransferase folate-binding domain; TIGRFAM: folate-binding protein YgfZ; Belongs to the GcvT family.
  
     0.627
groS
Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
       0.600
ADU47333.1
COGs: COG2099 Precorrin-6x reductase; InterPro IPR003723; KEGG: svi:Svir_17710 precorrin-6A reductase; PFAM: Precorrin-6x reductase CbiJ/CobK; PRIAM: Precorrin-6A reductase; SPTR: Precorrin-6x reductase CbiJ/CobK; TIGRFAM: precorrin-6x reductase; PFAM: Precorrin-6x reductase CbiJ/CobK; TIGRFAM: precorrin-6x reductase.
  
  
 0.582
ADU48831.1
KEGG: kse:Ksed_10780 hypothetical protein; SPTR: Secreted protein; PFAM: Protein of unknown function (DUF3515).
  
     0.576
ADU48056.1
KEGG: aau:AAur_1609 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.572
cobB
Hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
  
  
 0.552
ADU49012.1
Lipoprotein LpqB, GerMN domain; InterPro IPR019606: IPR018910; KEGG: kse:Ksed_08610 lipoprotein LpqB family protein/sporulation and spore germination protein; PFAM: Lipoprotein LpqB, GerMN domain; Lipoprotein LpqB, beta-propeller domain-like; SPTR: Lipoprotein LpqB family protein/sporulation and spore germination protein; PFAM: Lipoprotein LpqB beta-propeller domain; Sporulation and spore germination.
  
     0.549
ADU46724.1
GCN5-related N-acetyltransferase; COGs: COG1670 Acetyltransferase including N-acetylase of ribosomal protein; InterPro IPR000878: IPR000182; KEGG: tbi:Tbis_1840 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; SPTR: Putative uncharacterized protein; PFAM: Acetyltransferase (GNAT) family; Tetrapyrrole (Corrin/Porphyrin) Methylases.
  
  
 0.547
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.