| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADU46729.1 | whiB-3 | Intca_0168 | Intca_1018 | KEGG: kse:Ksed_01600 hypothetical protein; SPTR: Putative uncharacterized protein. | Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. | 0.466 |
| ADU47173.1 | whiB-3 | Intca_0628 | Intca_1018 | KEGG: bcv:Bcav_0722 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Lsr2. | Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. | 0.422 |
| ADU47542.1 | guaB | Intca_1019 | Intca_1021 | RNA polymerase, sigma-24 subunit, ECF subfamily; COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627: IPR013249: IPR014284; KEGG: sgr:SGR_2758 RNA polymerase sigma factor SigD; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; SPTR: RNA polymerase, sigma 32 subunit, RpoH; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; Belongs to the sigma-70 factor family. ECF subfamily. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.637 |
| ADU47542.1 | sigA | Intca_1019 | Intca_1505 | RNA polymerase, sigma-24 subunit, ECF subfamily; COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627: IPR013249: IPR014284; KEGG: sgr:SGR_2758 RNA polymerase sigma factor SigD; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; SPTR: RNA polymerase, sigma 32 subunit, RpoH; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; Belongs to the sigma-70 factor family. ECF subfamily. | RNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.520 |
| ADU47542.1 | whiB-3 | Intca_1019 | Intca_1018 | RNA polymerase, sigma-24 subunit, ECF subfamily; COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627: IPR013249: IPR014284; KEGG: sgr:SGR_2758 RNA polymerase sigma factor SigD; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; SPTR: RNA polymerase, sigma 32 subunit, RpoH; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; Belongs to the sigma-70 factor family. ECF subfamily. | Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. | 0.519 |
| ADU48273.1 | ADU48375.1 | Intca_1761 | Intca_1864 | COGs: COG2887 RecB family exonuclease; KEGG: kfl:Kfla_3207 RecB family exonuclease-like protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2800). | Phosphatidylinositol alpha-mannosyltransferase; COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: xce:Xcel_1660 glycosyl transferase group 1; PFAM: glycosyl transferase group 1; PRIAM: Phosphatidylinositol alpha-mannosyltransferase; SPTR: Putative glycosyltransferase; PFAM: Glycosyl transferases group 1. | 0.561 |
| ADU48273.1 | whiB-3 | Intca_1761 | Intca_1018 | COGs: COG2887 RecB family exonuclease; KEGG: kfl:Kfla_3207 RecB family exonuclease-like protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2800). | Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. | 0.524 |
| ADU48362.1 | guaB | Intca_1850 | Intca_1021 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.668 |
| ADU48362.1 | whiB-3 | Intca_1850 | Intca_1018 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. | 0.416 |
| ADU48375.1 | ADU48273.1 | Intca_1864 | Intca_1761 | Phosphatidylinositol alpha-mannosyltransferase; COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: xce:Xcel_1660 glycosyl transferase group 1; PFAM: glycosyl transferase group 1; PRIAM: Phosphatidylinositol alpha-mannosyltransferase; SPTR: Putative glycosyltransferase; PFAM: Glycosyl transferases group 1. | COGs: COG2887 RecB family exonuclease; KEGG: kfl:Kfla_3207 RecB family exonuclease-like protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2800). | 0.561 |
| ADU48375.1 | whiB-3 | Intca_1864 | Intca_1018 | Phosphatidylinositol alpha-mannosyltransferase; COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: xce:Xcel_1660 glycosyl transferase group 1; PFAM: glycosyl transferase group 1; PRIAM: Phosphatidylinositol alpha-mannosyltransferase; SPTR: Putative glycosyltransferase; PFAM: Glycosyl transferases group 1. | Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. | 0.425 |
| ADU48793.1 | whiB-3 | Intca_2284 | Intca_1018 | Protein of unknown function DUF2469; InterPro IPR019592; KEGG: sen:SACE_6046 hypothetical protein; PFAM: Protein of unknown function DUF2469; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2469). | Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. | 0.562 |
| ADU49401.1 | whiB-3 | Intca_2906 | Intca_1018 | Transglycosylase-like domain protein; InterPro IPR002482: IPR010618: IPR018392; KEGG: cai:Caci_5954 transglycosylase domain protein; PFAM: Transglycosylase-like domain protein; Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding LysM; SPTR: Putative uncharacterized protein; PFAM: Transglycosylase-like domain; LysM domain. | Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. | 0.438 |
| guaB | ADU47542.1 | Intca_1021 | Intca_1019 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | RNA polymerase, sigma-24 subunit, ECF subfamily; COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627: IPR013249: IPR014284; KEGG: sgr:SGR_2758 RNA polymerase sigma factor SigD; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; SPTR: RNA polymerase, sigma 32 subunit, RpoH; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; Belongs to the sigma-70 factor family. ECF subfamily. | 0.637 |
| guaB | ADU48362.1 | Intca_1021 | Intca_1850 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.668 |
| guaB | sigA | Intca_1021 | Intca_1505 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | RNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.577 |
| guaB | whiB-3 | Intca_1021 | Intca_1018 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. | 0.446 |
| sigA | ADU47542.1 | Intca_1505 | Intca_1019 | RNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | RNA polymerase, sigma-24 subunit, ECF subfamily; COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627: IPR013249: IPR014284; KEGG: sgr:SGR_2758 RNA polymerase sigma factor SigD; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; SPTR: RNA polymerase, sigma 32 subunit, RpoH; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; Belongs to the sigma-70 factor family. ECF subfamily. | 0.520 |
| sigA | guaB | Intca_1505 | Intca_1021 | RNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.577 |
| sigA | whiB-3 | Intca_1505 | Intca_1018 | RNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. | 0.535 |
