STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ADU47554.1Bifunctional deaminase-reductase domain protein; COGs: COG1985 Pyrimidine reductase riboflavin biosynthesis; InterPro IPR002734; KEGG: nca:Noca_1683 deaminase-reductase domain-containing protein; PFAM: bifunctional deaminase-reductase domain protein; SPTR: Bifunctional deaminase-reductase domain protein; PFAM: RibD C-terminal domain; TIGRFAM: riboflavin-specific deaminase C-terminal domain. (230 aa)    
Predicted Functional Partners:
ribA-2
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the GTP cyclohydrolase II family.
 
 
 0.946
ribA
GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.
 
 
 0.938
ADU48134.1
Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
 
  
0.919
ADU47553.1
KEGG: saq:Sare_2748 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised protein family (UPF0104).
 
     0.918
ADU48135.1
COGs: COG0307 Riboflavin synthase alpha chain; InterPro IPR001783; KEGG: sgr:SGR_6090 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein; PRIAM: Riboflavin synthase; SPTR: Putative riboflavin synthase alpha subunit; TIGRFAM: riboflavin synthase, alpha subunit; PFAM: Lumazine binding domain; TIGRFAM: riboflavin synthase, alpha subunit.
 
  
 0.893
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
 
 
 0.822
ADU47551.1
Hypothetical protein; COGs: COG0720 6-pyruvoyl-tetrahydropterin synthase; KEGG: tcu:Tcur_2746 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: 6-pyruvoyl tetrahydropterin synthase.
 
   
 0.813
ADU47550.1
FAD dependent oxidoreductase; COGs: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR006076; KEGG: nca:Noca_1679 dehydrogenase; PFAM: FAD dependent oxidoreductase; SPTR: Dehydrogenase; PFAM: FAD dependent oxidoreductase.
 
    0.803
ADU47552.1
COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: saq:Sare_2749 glycosyl transferase group 1; PFAM: glycosyl transferase group 1; SPTR: Glycosyl transferase group 1; PFAM: Glycosyl transferases group 1.
 
     0.797
ADU47548.1
KEGG: nml:Namu_0314 CDP-alcohol phosphatidyltransferase; SPTR: CDP-alcohol phosphatidyltransferase.
 
    0.784
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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