STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Coexpression
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[Homology]
Score
ADU47591.1Barbiturase; Responsible for the hydrolysis of barbituric acid (2,4,6- trihydroxy-1,3-pyrimidine), an intermediate in the oxidative catabolism of pyrimidines. Catalyzes the hydrolytic opening of the pyrimidine ring of barbituric acid to yield ureidomalonic acid; Belongs to the cyclic amide hydrolase (CyAH) family. (378 aa)    
Predicted Functional Partners:
ADU47592.1
COGs: COG0549 Carbamate kinase; InterPro IPR001048: IPR003964; KEGG: cai:Caci_1878 carbamate kinase; PFAM: aspartate/glutamate/uridylate kinase; PRIAM: Carbamate kinase; SPTR: Carbamate kinase; PFAM: Amino acid kinase family; TIGRFAM: carbamate kinase; Belongs to the carbamate kinase family.
 
     0.866
ADU47596.1
5-oxoprolinase (ATP-hydrolyzing); COGs: COG0146 N-methylhydantoinase B/acetone carboxylase alpha subunit; InterPro IPR003692; KEGG: cai:Caci_1877 hydantoinase B/oxoprolinase; PFAM: Hydantoinase B/oxoprolinase; PRIAM: 5-oxoprolinase (ATP-hydrolyzing); SPTR: N-methylhydantoinase (ATP-hydrolyzing) B 2; PFAM: Hydantoinase B/oxoprolinase.
 
     0.786
ADU47607.1
Transcriptional regulator, CdaR; COGs: COG3835 Sugar diacid utilization regulator; KEGG: tcu:Tcur_2969 transcriptional regulator, CdaR; SPTR: Transcriptional regulator.
 
     0.777
ADU47609.1
Protein of unknown function DUF1116; COGs: COG0074 Succinyl-CoA synthetase alpha subunit; InterPro IPR009499; KEGG: nml:Namu_5358 protein of unknown function DUF1116; PFAM: protein of unknown function DUF1116; SPTR: Putative uncharacterized protein; PFAM: CoA binding domain; CoA-ligase; Protein of unknown function (DUF1116).
 
     0.754
ADU47603.1
Carbon monoxide dehydrogenase subunit G; COGs: COG3427 conserved hypothetical protein; InterPro IPR010419; KEGG: rop:ROP_32810 hypothetical protein; PFAM: carbon monoxide dehydrogenase subunit G; SPTR: Putative uncharacterized protein; PFAM: Carbon monoxide dehydrogenase subunit G (CoxG).
 
     0.734
ADU47597.1
5-oxoprolinase (ATP-hydrolyzing); COGs: COG0145 N-methylhydantoinase A/acetone carboxylase beta subunit; InterPro IPR008040: IPR002821; KEGG: nca:Noca_1496 5-oxoprolinase (ATP-hydrolyzing); PFAM: Hydantoinase/oxoprolinase; Hydantoinaseoxoprolinase domain protein; PRIAM: 5-oxoprolinase (ATP-hydrolyzing); SPTR: N-methylhydantoinase (ATP-hydrolyzing) A 2; PFAM: Hydantoinase/oxoprolinase; Hydantoinase/oxoprolinase N-terminal region.
 
     0.714
ADU47608.1
KEGG: tbi:Tbis_2233 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2877).
 
     0.713
ADU47606.1
COGs: COG2233 Xanthine/uracil permease; InterPro IPR006043: IPR006042; KEGG: cai:Caci_1870 uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; SPTR: Putative uracyl permease; TIGRFAM: uracil-xanthine permease; PFAM: Permease family; TIGRFAM: uracil-xanthine permease.
 
     0.609
ADU47604.1
Xanthine dehydrogenase, molybdenum binding subunit apoprotein; COGs: COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL/CutL homologs; InterPro IPR000674: IPR008274; KEGG: svi:Svir_20920 xanthine dehydrogenase, molybdenum binding subunit apoprotein; PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; SPTR: Probable dehydrogenase/oxidase; PFAM: Molybdopterin-binding domain of aldehyde dehydrogenase; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain.
 
     0.603
ADU49522.1
COGs: COG0777 Acetyl-CoA carboxylase beta subunit; InterPro IPR011762: IPR011763: IPR000438: IPR000022; KEGG: nca:Noca_4502 carboxyl transferase; PFAM: carboxyl transferase; SPTR: Carboxyl transferase; PFAM: Carboxyl transferase domain; TIGRFAM: acetyl-CoA carboxylase, carboxyl transferase, beta subunit.
 
     0.459
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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