| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADU47587.1 | ADU47608.1 | Intca_1064 | Intca_1087 | KEGG: bcv:Bcav_3015 hypothetical protein; SPTR: Putative uncharacterized protein. | KEGG: tbi:Tbis_2233 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2877). | 0.583 |
| ADU47587.1 | ADU47950.1 | Intca_1064 | Intca_1435 | KEGG: bcv:Bcav_3015 hypothetical protein; SPTR: Putative uncharacterized protein. | KEGG: msm:MSMEG_1644 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.561 |
| ADU47587.1 | ADU48468.1 | Intca_1064 | Intca_1957 | KEGG: bcv:Bcav_3015 hypothetical protein; SPTR: Putative uncharacterized protein. | KEGG: kra:Krad_3217 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.551 |
| ADU47587.1 | ADU49093.1 | Intca_1064 | Intca_2588 | KEGG: bcv:Bcav_3015 hypothetical protein; SPTR: Putative uncharacterized protein. | KEGG: tcu:Tcur_1191 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.616 |
| ADU47591.1 | ADU47592.1 | Intca_1068 | Intca_1069 | Barbiturase; Responsible for the hydrolysis of barbituric acid (2,4,6- trihydroxy-1,3-pyrimidine), an intermediate in the oxidative catabolism of pyrimidines. Catalyzes the hydrolytic opening of the pyrimidine ring of barbituric acid to yield ureidomalonic acid; Belongs to the cyclic amide hydrolase (CyAH) family. | COGs: COG0549 Carbamate kinase; InterPro IPR001048: IPR003964; KEGG: cai:Caci_1878 carbamate kinase; PFAM: aspartate/glutamate/uridylate kinase; PRIAM: Carbamate kinase; SPTR: Carbamate kinase; PFAM: Amino acid kinase family; TIGRFAM: carbamate kinase; Belongs to the carbamate kinase family. | 0.866 |
| ADU47591.1 | ADU47596.1 | Intca_1068 | Intca_1075 | Barbiturase; Responsible for the hydrolysis of barbituric acid (2,4,6- trihydroxy-1,3-pyrimidine), an intermediate in the oxidative catabolism of pyrimidines. Catalyzes the hydrolytic opening of the pyrimidine ring of barbituric acid to yield ureidomalonic acid; Belongs to the cyclic amide hydrolase (CyAH) family. | 5-oxoprolinase (ATP-hydrolyzing); COGs: COG0146 N-methylhydantoinase B/acetone carboxylase alpha subunit; InterPro IPR003692; KEGG: cai:Caci_1877 hydantoinase B/oxoprolinase; PFAM: Hydantoinase B/oxoprolinase; PRIAM: 5-oxoprolinase (ATP-hydrolyzing); SPTR: N-methylhydantoinase (ATP-hydrolyzing) B 2; PFAM: Hydantoinase B/oxoprolinase. | 0.786 |
| ADU47591.1 | ADU47606.1 | Intca_1068 | Intca_1085 | Barbiturase; Responsible for the hydrolysis of barbituric acid (2,4,6- trihydroxy-1,3-pyrimidine), an intermediate in the oxidative catabolism of pyrimidines. Catalyzes the hydrolytic opening of the pyrimidine ring of barbituric acid to yield ureidomalonic acid; Belongs to the cyclic amide hydrolase (CyAH) family. | COGs: COG2233 Xanthine/uracil permease; InterPro IPR006043: IPR006042; KEGG: cai:Caci_1870 uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; SPTR: Putative uracyl permease; TIGRFAM: uracil-xanthine permease; PFAM: Permease family; TIGRFAM: uracil-xanthine permease. | 0.609 |
| ADU47591.1 | ADU47607.1 | Intca_1068 | Intca_1086 | Barbiturase; Responsible for the hydrolysis of barbituric acid (2,4,6- trihydroxy-1,3-pyrimidine), an intermediate in the oxidative catabolism of pyrimidines. Catalyzes the hydrolytic opening of the pyrimidine ring of barbituric acid to yield ureidomalonic acid; Belongs to the cyclic amide hydrolase (CyAH) family. | Transcriptional regulator, CdaR; COGs: COG3835 Sugar diacid utilization regulator; KEGG: tcu:Tcur_2969 transcriptional regulator, CdaR; SPTR: Transcriptional regulator. | 0.777 |
| ADU47591.1 | ADU47608.1 | Intca_1068 | Intca_1087 | Barbiturase; Responsible for the hydrolysis of barbituric acid (2,4,6- trihydroxy-1,3-pyrimidine), an intermediate in the oxidative catabolism of pyrimidines. Catalyzes the hydrolytic opening of the pyrimidine ring of barbituric acid to yield ureidomalonic acid; Belongs to the cyclic amide hydrolase (CyAH) family. | KEGG: tbi:Tbis_2233 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2877). | 0.713 |
| ADU47591.1 | ADU47609.1 | Intca_1068 | Intca_1088 | Barbiturase; Responsible for the hydrolysis of barbituric acid (2,4,6- trihydroxy-1,3-pyrimidine), an intermediate in the oxidative catabolism of pyrimidines. Catalyzes the hydrolytic opening of the pyrimidine ring of barbituric acid to yield ureidomalonic acid; Belongs to the cyclic amide hydrolase (CyAH) family. | Protein of unknown function DUF1116; COGs: COG0074 Succinyl-CoA synthetase alpha subunit; InterPro IPR009499; KEGG: nml:Namu_5358 protein of unknown function DUF1116; PFAM: protein of unknown function DUF1116; SPTR: Putative uncharacterized protein; PFAM: CoA binding domain; CoA-ligase; Protein of unknown function (DUF1116). | 0.754 |
| ADU47592.1 | ADU47591.1 | Intca_1069 | Intca_1068 | COGs: COG0549 Carbamate kinase; InterPro IPR001048: IPR003964; KEGG: cai:Caci_1878 carbamate kinase; PFAM: aspartate/glutamate/uridylate kinase; PRIAM: Carbamate kinase; SPTR: Carbamate kinase; PFAM: Amino acid kinase family; TIGRFAM: carbamate kinase; Belongs to the carbamate kinase family. | Barbiturase; Responsible for the hydrolysis of barbituric acid (2,4,6- trihydroxy-1,3-pyrimidine), an intermediate in the oxidative catabolism of pyrimidines. Catalyzes the hydrolytic opening of the pyrimidine ring of barbituric acid to yield ureidomalonic acid; Belongs to the cyclic amide hydrolase (CyAH) family. | 0.866 |
| ADU47592.1 | ADU47608.1 | Intca_1069 | Intca_1087 | COGs: COG0549 Carbamate kinase; InterPro IPR001048: IPR003964; KEGG: cai:Caci_1878 carbamate kinase; PFAM: aspartate/glutamate/uridylate kinase; PRIAM: Carbamate kinase; SPTR: Carbamate kinase; PFAM: Amino acid kinase family; TIGRFAM: carbamate kinase; Belongs to the carbamate kinase family. | KEGG: tbi:Tbis_2233 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2877). | 0.510 |
| ADU47592.1 | ADU47609.1 | Intca_1069 | Intca_1088 | COGs: COG0549 Carbamate kinase; InterPro IPR001048: IPR003964; KEGG: cai:Caci_1878 carbamate kinase; PFAM: aspartate/glutamate/uridylate kinase; PRIAM: Carbamate kinase; SPTR: Carbamate kinase; PFAM: Amino acid kinase family; TIGRFAM: carbamate kinase; Belongs to the carbamate kinase family. | Protein of unknown function DUF1116; COGs: COG0074 Succinyl-CoA synthetase alpha subunit; InterPro IPR009499; KEGG: nml:Namu_5358 protein of unknown function DUF1116; PFAM: protein of unknown function DUF1116; SPTR: Putative uncharacterized protein; PFAM: CoA binding domain; CoA-ligase; Protein of unknown function (DUF1116). | 0.739 |
| ADU47596.1 | ADU47591.1 | Intca_1075 | Intca_1068 | 5-oxoprolinase (ATP-hydrolyzing); COGs: COG0146 N-methylhydantoinase B/acetone carboxylase alpha subunit; InterPro IPR003692; KEGG: cai:Caci_1877 hydantoinase B/oxoprolinase; PFAM: Hydantoinase B/oxoprolinase; PRIAM: 5-oxoprolinase (ATP-hydrolyzing); SPTR: N-methylhydantoinase (ATP-hydrolyzing) B 2; PFAM: Hydantoinase B/oxoprolinase. | Barbiturase; Responsible for the hydrolysis of barbituric acid (2,4,6- trihydroxy-1,3-pyrimidine), an intermediate in the oxidative catabolism of pyrimidines. Catalyzes the hydrolytic opening of the pyrimidine ring of barbituric acid to yield ureidomalonic acid; Belongs to the cyclic amide hydrolase (CyAH) family. | 0.786 |
| ADU47596.1 | ADU47607.1 | Intca_1075 | Intca_1086 | 5-oxoprolinase (ATP-hydrolyzing); COGs: COG0146 N-methylhydantoinase B/acetone carboxylase alpha subunit; InterPro IPR003692; KEGG: cai:Caci_1877 hydantoinase B/oxoprolinase; PFAM: Hydantoinase B/oxoprolinase; PRIAM: 5-oxoprolinase (ATP-hydrolyzing); SPTR: N-methylhydantoinase (ATP-hydrolyzing) B 2; PFAM: Hydantoinase B/oxoprolinase. | Transcriptional regulator, CdaR; COGs: COG3835 Sugar diacid utilization regulator; KEGG: tcu:Tcur_2969 transcriptional regulator, CdaR; SPTR: Transcriptional regulator. | 0.729 |
| ADU47596.1 | ADU47608.1 | Intca_1075 | Intca_1087 | 5-oxoprolinase (ATP-hydrolyzing); COGs: COG0146 N-methylhydantoinase B/acetone carboxylase alpha subunit; InterPro IPR003692; KEGG: cai:Caci_1877 hydantoinase B/oxoprolinase; PFAM: Hydantoinase B/oxoprolinase; PRIAM: 5-oxoprolinase (ATP-hydrolyzing); SPTR: N-methylhydantoinase (ATP-hydrolyzing) B 2; PFAM: Hydantoinase B/oxoprolinase. | KEGG: tbi:Tbis_2233 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2877). | 0.523 |
| ADU47596.1 | ADU47609.1 | Intca_1075 | Intca_1088 | 5-oxoprolinase (ATP-hydrolyzing); COGs: COG0146 N-methylhydantoinase B/acetone carboxylase alpha subunit; InterPro IPR003692; KEGG: cai:Caci_1877 hydantoinase B/oxoprolinase; PFAM: Hydantoinase B/oxoprolinase; PRIAM: 5-oxoprolinase (ATP-hydrolyzing); SPTR: N-methylhydantoinase (ATP-hydrolyzing) B 2; PFAM: Hydantoinase B/oxoprolinase. | Protein of unknown function DUF1116; COGs: COG0074 Succinyl-CoA synthetase alpha subunit; InterPro IPR009499; KEGG: nml:Namu_5358 protein of unknown function DUF1116; PFAM: protein of unknown function DUF1116; SPTR: Putative uncharacterized protein; PFAM: CoA binding domain; CoA-ligase; Protein of unknown function (DUF1116). | 0.547 |
| ADU47606.1 | ADU47591.1 | Intca_1085 | Intca_1068 | COGs: COG2233 Xanthine/uracil permease; InterPro IPR006043: IPR006042; KEGG: cai:Caci_1870 uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; SPTR: Putative uracyl permease; TIGRFAM: uracil-xanthine permease; PFAM: Permease family; TIGRFAM: uracil-xanthine permease. | Barbiturase; Responsible for the hydrolysis of barbituric acid (2,4,6- trihydroxy-1,3-pyrimidine), an intermediate in the oxidative catabolism of pyrimidines. Catalyzes the hydrolytic opening of the pyrimidine ring of barbituric acid to yield ureidomalonic acid; Belongs to the cyclic amide hydrolase (CyAH) family. | 0.609 |
| ADU47606.1 | ADU47607.1 | Intca_1085 | Intca_1086 | COGs: COG2233 Xanthine/uracil permease; InterPro IPR006043: IPR006042; KEGG: cai:Caci_1870 uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; SPTR: Putative uracyl permease; TIGRFAM: uracil-xanthine permease; PFAM: Permease family; TIGRFAM: uracil-xanthine permease. | Transcriptional regulator, CdaR; COGs: COG3835 Sugar diacid utilization regulator; KEGG: tcu:Tcur_2969 transcriptional regulator, CdaR; SPTR: Transcriptional regulator. | 0.677 |
| ADU47606.1 | ADU47608.1 | Intca_1085 | Intca_1087 | COGs: COG2233 Xanthine/uracil permease; InterPro IPR006043: IPR006042; KEGG: cai:Caci_1870 uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; SPTR: Putative uracyl permease; TIGRFAM: uracil-xanthine permease; PFAM: Permease family; TIGRFAM: uracil-xanthine permease. | KEGG: tbi:Tbis_2233 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2877). | 0.518 |