STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU47618.1Transcriptional regulator, IclR family; COGs: COG1414 Transcriptional regulator; InterPro IPR005471: IPR014757; KEGG: tcu:Tcur_0533 transcriptional regulator, IclR family; PFAM: regulatory protein IclR; Transcriptional regulator IclR; SMART: regulatory protein IclR; SPTR: Transcriptional regulator, IclR family; PFAM: IclR helix-turn-helix domain; Bacterial transcriptional regulator. (268 aa)    
Predicted Functional Partners:
ADU47619.1
Transcriptional regulator, IclR family; COGs: COG1414 Transcriptional regulator; InterPro IPR005471: IPR014757; KEGG: tcu:Tcur_0532 transcriptional regulator, IclR family; PFAM: regulatory protein IclR; Transcriptional regulator IclR; SMART: regulatory protein IclR; SPTR: Transcriptional regulator, IclR family; PFAM: IclR helix-turn-helix domain; Bacterial transcriptional regulator.
 
    
0.652
ADU47642.1
GntR domain protein; COGs: COG2186 Transcriptional regulators; InterPro IPR000524: IPR011711; KEGG: art:Arth_0271 GntR family transcriptional regulator; PFAM: GntR domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: Transcriptional regulator, GntR family; PFAM: Bacterial regulatory proteins, gntR family; FCD domain.
  
    0.531
ADU47614.1
4-oxalocrotonate decarboxylase; COGs: COG3971 2-keto-4-pentenoate hydratase; InterPro IPR002529; KEGG: mjl:Mjls_4208 4-oxalocrotonate decarboxylase; PFAM: fumarylacetoacetate (FAA) hydrolase; PRIAM: 4-oxalocrotonate decarboxylase; SPTR: 4-oxalocrotonate decarboxylase; PFAM: Fumarylacetoacetate (FAA) hydrolase family.
 
    0.526
ADU47353.1
COGs: COG2049 Allophanate hydrolase subunit 1; InterPro IPR003833: IPR010016; KEGG: svi:Svir_06200 conserved hypothetical protein TIGR00370; PFAM: Allophanate hydrolase subunit 1; SMART: Allophanate hydrolase subunit 1; SPTR: Putative uncharacterized protein; PFAM: Allophanate hydrolase subunit 1; TIGRFAM: conserved hypothetical protein TIGR00370.
  
    0.514
ADU47617.1
COGs: COG3971 2-keto-4-pentenoate hydratase; InterPro IPR002529; KEGG: amd:AMED_8623 2-keto-4-pentenoate hydratase; PFAM: fumarylacetoacetate (FAA) hydrolase; PRIAM: 2-oxopent-4-enoate hydratase; SPTR: 2-oxopent-4-enoate hydratase; PFAM: Fumarylacetoacetate (FAA) hydrolase family; TIGRFAM: 2-oxopent-4-enoate hydratase.
 
    0.503
ADU47354.1
Urea amidolyase related protein; COGs: COG1984 Allophanate hydrolase subunit 2; InterPro IPR003778; KEGG: kfl:Kfla_6553 UreA amidolyase related protein; PFAM: Allophanate hydrolase subunit 2; SMART: Allophanate hydrolase subunit 2; SPTR: Urea amidolyase related protein; TIGRFAM: urea amidolyase related protein; PFAM: Allophanate hydrolase subunit 2; TIGRFAM: biotin-dependent carboxylase uncharacterized domain.
  
    0.501
ADU47836.1
Transcriptional regulator, IclR family; COGs: COG1414 Transcriptional regulator; InterPro IPR005471: IPR014757; KEGG: nca:Noca_1292 regulatory proteins, IclR; PFAM: regulatory protein IclR; SMART: regulatory protein IclR; SPTR: IclR family transcriptional regulator; PFAM: IclR helix-turn-helix domain.
  
     0.500
ADU47616.1
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
 
     0.492
ADU47613.1
4-oxalocrotonate tautomerase family enzyme; InterPro IPR004370: IPR018191; KEGG: nfa:nfa30440 putative isomerase; PFAM: 4-oxalocrotonate tautomerase; SPTR: Putative isomerase; TIGRFAM: 4-oxalocrotonate tautomerase family enzyme; PFAM: Tautomerase enzyme; TIGRFAM: 4-oxalocrotonate tautomerase family enzyme.
 
     0.482
ADU47470.1
Transcriptional regulator, GntR family; COGs: COG2186 Transcriptional regulators; InterPro IPR000524: IPR011711; KEGG: sro:Sros_2470 transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; GntR domain protein; SMART: regulatory protein GntR HTH; SPTR: Regulatory protein GntR HTH; PFAM: Bacterial regulatory proteins, gntR family; FCD domain.
  
    0.471
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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