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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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ADU47624.1Catechol 2,3-dioxygenase; InterPro IPR004360: IPR000486; KEGG: tcu:Tcur_0529 catechol 2,3 dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: Catechol 2,3 dioxygenase; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; TIGRFAM: catechol 2,3 dioxygenase. (305 aa)    
Predicted Functional Partners:
ADU47611.1
2-hydroxymuconate semialdehyde hydrolase; COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000073; KEGG: tcu:Tcur_0531 alpha/beta hydrolase fold protein; PFAM: alpha/beta hydrolase fold; SPTR: 2-hydroxymuconic semialdehyde hydrolase; PFAM: alpha/beta hydrolase fold.
  
 
 0.974
ADU47613.1
4-oxalocrotonate tautomerase family enzyme; InterPro IPR004370: IPR018191; KEGG: nfa:nfa30440 putative isomerase; PFAM: 4-oxalocrotonate tautomerase; SPTR: Putative isomerase; TIGRFAM: 4-oxalocrotonate tautomerase family enzyme; PFAM: Tautomerase enzyme; TIGRFAM: 4-oxalocrotonate tautomerase family enzyme.
 
  
 0.974
ADU49656.1
COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000639: IPR000073; KEGG: nca:Noca_0210 alpha/beta hydrolase fold; PFAM: alpha/beta hydrolase fold; SPTR: Alpha/beta hydrolase fold; PFAM: alpha/beta hydrolase fold.
  
 
 0.966
ADU47625.1
Ferredoxin; InterPro IPR001041: IPR006058; KEGG: tcu:Tcur_0528 ferredoxin; PFAM: ferredoxin; SPTR: Ferredoxin; PFAM: 2Fe-2S iron-sulfur cluster binding domain.
 
     0.932
ADU47612.1
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590: IPR016160; KEGG: tcu:Tcur_0539 betaine-aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: Betaine-aldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase family.
 
  
 0.917
ADU47623.1
Protein of unknown function DUF336; COGs: COG3193 Uncharacterized protein possibly involved in utilization of glycolate and propanediol; InterPro IPR005624; KEGG: bts:Btus_0972 protein of unknown function DUF336; PFAM: protein of unknown function DUF336; SPTR: Putative uncharacterized protein; PFAM: Domain of unknown function (DUF336).
 
     0.871
ADU47616.1
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
 
   
 0.798
ADU47614.1
4-oxalocrotonate decarboxylase; COGs: COG3971 2-keto-4-pentenoate hydratase; InterPro IPR002529; KEGG: mjl:Mjls_4208 4-oxalocrotonate decarboxylase; PFAM: fumarylacetoacetate (FAA) hydrolase; PRIAM: 4-oxalocrotonate decarboxylase; SPTR: 4-oxalocrotonate decarboxylase; PFAM: Fumarylacetoacetate (FAA) hydrolase family.
 
   
 0.796
ADU47617.1
COGs: COG3971 2-keto-4-pentenoate hydratase; InterPro IPR002529; KEGG: amd:AMED_8623 2-keto-4-pentenoate hydratase; PFAM: fumarylacetoacetate (FAA) hydrolase; PRIAM: 2-oxopent-4-enoate hydratase; SPTR: 2-oxopent-4-enoate hydratase; PFAM: Fumarylacetoacetate (FAA) hydrolase family; TIGRFAM: 2-oxopent-4-enoate hydratase.
 
   
 0.792
ADU47615.1
4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
 
   
 0.772
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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