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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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ADU47644.16-phosphogluconate dehydrogenase NAD-binding protein; COGs: COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase; InterPro IPR006115: IPR002204; KEGG: art:Arth_0273 6-phosphogluconate dehydrogenase, NAD-binding; PFAM: 6-phosphogluconate dehydrogenase NAD-binding; SPTR: 6-phosphogluconate dehydrogenase, NAD-binding; PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase. (297 aa)    
Predicted Functional Partners:
ADU47643.1
Type III effector Hrp-dependent outer domain protein; COGs: COG3395 conserved hypothetical protein; InterPro IPR010737; KEGG: cdi:DIP2080 hypothetical protein; PFAM: type III effector Hrp-dependent outers; SPTR: YgbK domain protein; PFAM: Protein of unknown function, DUF1537.
  
 0.993
ADU48271.1
Methylmalonate-semialdehyde dehydrogenase (acylating); COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR016160: IPR015590: IPR010061; KEGG: msv:Mesil_1872 methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: Methylmalonate-semialdehyde dehydrogenase; TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde dehydrogenase family; TIGRFAM: methylmalonic acid semialdehyde dehydrogenase.
  
 
 0.917
ADU47739.1
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590: IPR016160; KEGG: bcv:Bcav_0209 aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: Putative aldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family.
  
 
 0.916
ADU48656.1
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590: IPR012394: IPR016160; KEGG: nda:Ndas_1930 aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: Aldehyde Dehydrogenase; PFAM: Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family.
  
 
 0.916
ADU49369.1
COGs: COG0160 4-aminobutyrate aminotransferase and related aminotransferase; InterPro IPR005814: IPR004632; KEGG: nml:Namu_4960 4-aminobutyrate aminotransferase; PFAM: aminotransferase class-III; SPTR: 4-aminobutyrate aminotransferase; TIGRFAM: 4-aminobutyrate aminotransferase; PFAM: Aminotransferase class-III; TIGRFAM: 4-aminobutyrate aminotransferase, prokaryotic type; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
  0.900
ADU47746.1
Biotin carboxyl carrier protein; COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterProIPR005481: IPR005479: IPR005482: IPR000089: IPR 001882: IPR011761: IPR011764; KEGG: kse:Ksed_08190 acetyl/propionyl-CoA carboxylase, alpha subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; biotin/lipoyl attachment domain-containing protein; SPTR: Putative acyl-CoA carboxylase, alpha subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; Biotin carboxylase C-te [...]
  
 
 0.840
ADU47645.1
COGs: COG2610 H+/gluconate symporter and related permease; InterPro IPR003474; KEGG: spe:Spro_1488 inner membrane permease YgbN; PFAM: Gluconate transporter; SPTR: Gluconate transporter; TIGRFAM: gluconate transporter; PFAM: GntP family permease; TIGRFAM: gluconate transporter.
  
  
 0.839
ADU46915.1
COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: cai:Caci_4507 acetate/CoA ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: Acetate/CoA ligase; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme.
  
 
 0.817
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.817
ADU48771.1
COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR020845: IPR000873; KEGG: sro:Sros_1890 propionate--CoA ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: Acetyl-CoA synthetase; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme.
  
 
 0.817
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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