STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Coexpression
Experiments
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[Homology]
Score
ADU47682.1Transcriptional regulator, LysR family; COGs: COG0583 Transcriptional regulator; InterPro IPR000847: IPR005119; KEGG: ade:Adeh_2212 LysR family transcriptional regulator; PFAM: LysR substrate-binding; regulatory protein LysR; SPTR: Transcriptional regulator, LysR family; PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain. (293 aa)    
Predicted Functional Partners:
ADU48642.1
Transcriptional regulator, LysR family; COGs: COG0583 Transcriptional regulator; InterPro IPR000847: IPR005119; KEGG: nca:Noca_0392 LysR family transcriptional regulator; PFAM: LysR substrate-binding; regulatory protein LysR; SPTR: Transcriptional regulator, LysR family; PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain.
  
     0.753
ADU47107.1
Transcriptional regulator, LysR family; COGs: COG0583 Transcriptional regulator; InterPro IPR000847: IPR005119; KEGG: sro:Sros_3515 LysR family regulatory protein; PFAM: regulatory protein LysR; LysR substrate-binding; SPTR: LysR family regulatory protein; manually curated; PFAM: LysR substrate binding domain; Bacterial regulatory helix-turn-helix protein, lysR family.
  
     0.724
ADU47511.1
Transcriptional regulator, LysR family; COGs: COG0583 Transcriptional regulator; InterPro IPR000847: IPR005119; KEGG: gbr:Gbro_4403 LysR substrate-binding protein; PFAM: LysR substrate-binding; regulatory protein LysR; SPTR: Putative LysR-family transcriptional regulator; PFAM: LysR substrate binding domain; Bacterial regulatory helix-turn-helix protein, lysR family.
  
     0.688
ADU48157.1
Glutamate synthase (NADH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterProIPR017932: IPR000583: IPR006982: IPR002932: IPR 002489; KEGG: kfl:Kfla_3074 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Putative glutamate synthase (NADPH) large subunit; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
     
 0.565
psuG
Indigoidine synthase A family protein; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family.
       0.542
ADU47684.1
PfkB domain protein; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: sen:SACE_1230 sugar kinase, phosphofructokinase; PFAM: PfkB domain protein; SPTR: Sugar kinase, possible phosphofructokinase; PFAM: pfkB family carbohydrate kinase.
       0.542
ADU50060.1
Transcriptional regulator, LysR family; COGs: COG0583 Transcriptional regulator; InterPro IPR000847: IPR005119; KEGG: sen:SACE_0264 LysR family transcriptional regulator; PFAM: LysR substrate-binding; regulatory protein LysR; SPTR: Probable transcriptional regulator, LysR family; PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain.
  
     0.508
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.443
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.421
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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