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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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ADU47721.1InterPro IPR011138; KEGG: nca:Noca_3551 succinate dehydrogenase subunit C; SPTR: Succinate dehydrogenase, cytochrome b558 subunit; TIGRFAM: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family; TIGRFAM: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family. (241 aa)    
Predicted Functional Partners:
ADU47719.1
COGs: COG0479 Succinate dehydrogenase/fumarate reductase Fe-S protein subunit; InterPro IPR006058: IPR017900: IPR017896: IPR004489; KEGG: nca:Noca_3553 succinate dehydrogenase/fumarate reductase iron-sulfur subunit; SPTR: Succinate dehydrogenase; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein.
 
 0.999
ADU47720.1
COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR003953: IPR004112: IPR011280; KEGG: nca:Noca_3552 succinate dehydrogenase flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; PRIAM: Succinate dehydrogenase; SPTR: Succinate dehydrogenase subunit A; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: domain; FAD binding domain; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit, Bacillus subtilis subgroup.
 
 0.999
ADU49201.1
Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
    
 0.920
sucC
succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
    
 0.918
sucD
succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
    
 0.913
fumC
Fumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
     
  0.900
ADU48757.1
Succinate semialdehyde dehydrogenase; COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR016160: IPR015590; KEGG: svi:Svir_30180 succinate semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: Succinate-semialdehyde dehydrogenase; PFAM: Aldehyde dehydrogenase family; TIGRFAM: succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 
  0.900
ADU47833.1
Fumarylacetoacetate hydrolase; COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR005959: IPR015377: IPR002529; KEGG: kse:Ksed_10630 fumarylacetoacetate hydrolase; PFAM: Domain of unknown function DUF1969; fumarylacetoacetate (FAA) hydrolase; PRIAM: Fumarylacetoacetase; SPTR: Putative fumarylacetoacetase; TIGRFAM: fumarylacetoacetase; PFAM: Domain of unknown function (DUF1969); Fumarylacetoacetate (FAA) hydrolase family; TIGRFAM: fumarylacetoacetase.
    
  0.805
ADU49912.1
Ureidoglycolate lyase; COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR002529; KEGG: svi:Svir_20690 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase; PFAM: fumarylacetoacetate (FAA) hydrolase; PRIAM: Ureidoglycolate lyase; SPTR: Fumarylacetoacetate hydrolase domain-containing protein 2A; PFAM: Fumarylacetoacetate (FAA) hydrolase family.
    
  0.805
argH
COGs: COG0165 Argininosuccinate lyase; InterPro IPR003031: IPR000362: IPR020557: IPR009049; KEGG: ske:Sked_22260 argininosuccinate lyase; PFAM: fumarate lyase; SPTR: Argininosuccinate lyase; TIGRFAM: argininosuccinate lyase; PFAM: Lyase; TIGRFAM: argininosuccinate lyase.
     
  0.800
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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