STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU47734.1COGs: COG0213 Thymidine phosphorylase; InterProIPR017459: IPR000312: IPR013102: IPR017872: IPR 018090: IPR000053; KEGG: bcv:Bcav_2940 pyrimidine-nucleoside phosphorylase; PFAM: glycosyl transferase family 3; Glycosyl transferase, family 3-like; Pyrimidine nucleoside phosphorylase domain; PRIAM: Thymidine phosphorylase; SPTR: Thymidine phosphorylase; TIGRFAM: pyrimidine-nucleoside phosphorylase; PFAM: Pyrimidine nucleoside phosphorylase C-terminal domain; Glycosyl transferase family, a/b domain; Glycosyl transferase family, helical bundle domain; TIGRFAM: pyrimidine-nucleoside phosphorylase. (432 aa)    
Predicted Functional Partners:
ADU47733.1
COGs: COG0295 Cytidine deaminase; InterPro IPR002125: IPR016192: IPR006262; KEGG: gob:Gobs_4399 cytidine deaminase; PFAM: CMP/dCMP deaminase zinc-binding; SPTR: Cytidine deaminase; TIGRFAM: cytidine deaminase; PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region; TIGRFAM: cytidine deaminase, homotetrameric.
 
 0.998
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
 
 
 0.970
ADU47743.1
Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
 
  
 0.968
ADU48453.1
COGs: COG1435 Thymidine kinase; InterPro IPR001267: IPR020634; KEGG: kse:Ksed_15850 thymidine kinase; PFAM: thymidine kinase; PRIAM: Thymidine kinase; SPTR: Thymidine kinase; PFAM: Thymidine kinase.
    
 0.933
ADU47740.1
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate.
 
 
 0.931
ADU49724.1
5'-Nucleotidase domain-containing protein; COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR006179: IPR004843: IPR008334; KEGG: sna:Snas_4270 5'-nucleotidase domain-containing protein; PFAM: 5'-Nucleotidase domain-containing protein; metallophosphoesterase; SPTR: Putative 5'-nucleotidase; PFAM: Calcineurin-like phosphoesterase; 5'-nucleotidase, C-terminal domain; Belongs to the 5'-nucleotidase family.
 
  
 0.919
pyrR
Uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
     
 0.915
psuG
Indigoidine synthase A family protein; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family.
    
  0.902
add
COGs: COG1816 Adenosine deaminase; InterPro IPR001365: IPR006330; KEGG: sro:Sros_1279 adenosine deaminase; PFAM: adenosine/AMP deaminase; PRIAM: Adenosine deaminase; SPTR: Adenosine deaminase; TIGRFAM: adenosine deaminase; PFAM: Adenosine/AMP deaminase; TIGRFAM: adenosine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
 
   
 0.752
era
GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
  
    0.746
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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