STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADU47743.1Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (277 aa)    
Predicted Functional Partners:
ADU47742.1
Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; COGs: COG1109 Phosphomannomutase; InterProIPR005844: IPR005845: IPR005846: IPR005843: IPR 016066; KEGG: kse:Ksed_08160 phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; SPTR: Putative phosphomannomutase; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutas [...]
 
 
 0.955
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
 
 0.947
ADU48504.1
PfkB domain protein; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611: IPR002173; KEGG: tbi:Tbis_1286 PfkB domain-containing protein; PFAM: PfkB domain protein; SPTR: Putative carbohydrate kinase; PFAM: pfkB family carbohydrate kinase.
    
 0.934
ADU47143.1
COGs: COG0634 Hypoxanthine-guanine phosphoribosyltransferase; InterPro IPR000836: IPR005904; KEGG: kse:Ksed_24790 hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; PRIAM: Hypoxanthine phosphoribosyltransferase; SPTR: Putative hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; manually curated; PFAM: Phosphoribosyl transferase domain; TIGRFAM: hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 0.932
add
COGs: COG1816 Adenosine deaminase; InterPro IPR001365: IPR006330; KEGG: sro:Sros_1279 adenosine deaminase; PFAM: adenosine/AMP deaminase; PRIAM: Adenosine deaminase; SPTR: Adenosine deaminase; TIGRFAM: adenosine deaminase; PFAM: Adenosine/AMP deaminase; TIGRFAM: adenosine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
 
 
 0.930
ADU49293.1
COGs: COG1816 Adenosine deaminase; InterPro IPR006330: IPR001365: IPR006650; KEGG: kse:Ksed_21160 adenosine deaminase; PFAM: adenosine/AMP deaminase; PRIAM: Adenosine deaminase; SPTR: Putative adenosine deaminase; TIGRFAM: adenosine deaminase; PFAM: Adenosine/AMP deaminase; TIGRFAM: adenosine deaminase.
  
 
 0.919
ADU47996.1
COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680; KEGG: msv:Mesil_1795 guanine deaminase; PFAM: amidohydrolase; SPTR: Amidohydrolase; PFAM: Amidohydrolase family; TIGRFAM: guanine deaminase.
  
 
 0.909
ADU47838.1
Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
    
 0.908
ADU47998.1
COGs: COG4631 Xanthine dehydrogenase molybdopterin-binding subunit B; InterPro IPR014309: IPR000674: IPR008274; KEGG: nca:Noca_1637 xanthine oxidase; PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; PRIAM: Xanthine oxidase; SPTR: Xanthine oxidase; TIGRFAM: xanthine dehydrogenase, molybdopterin binding subunit; PFAM: Molybdopterin-binding domain of aldehyde dehydrogenase; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; TIGRFAM: xanthine dehydrogenase, molybdopterin binding subunit.
   
 
 0.907
ADU47828.1
2',3'-cyclic-nucleotide 2'-phosphodiesterase; COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterProIPR006311: IPR006179: IPR022272: IPR004843: IPR 008334: IPR017909; KEGG: nca:Noca_1299 5'-nucleotidase domain-containing protein; PFAM: 5'-Nucleotidase domain-containing protein; metallophosphoesterase; PRIAM: 2',3'-cyclic-nucleotide 2'-phosphodiesterase; SPTR: 5'-Nucleotidase domain protein; PFAM: Calcineurin-like phosphoesterase; 5'-nucleotidase, C-terminal domain; Belongs to the 5'-nucleotidase family.
  
 
 0.906
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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