| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADU46669.1 | ADU47747.1 | Intca_0108 | Intca_1229 | COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR001395; KEGG: kfl:Kfla_0935 aldo/keto reductase; PFAM: aldo/keto reductase; SPTR: Aldo/keto reductase; PFAM: Aldo/keto reductase family. | COGs: COG0656 Aldo/keto reductase related to diketogulonate reductase; InterPro IPR001395: IPR018170: IPR020471; KEGG: tcu:Tcur_1587 2,5-didehydrogluconate reductase; PFAM: aldo/keto reductase; PRIAM: 2,5-didehydrogluconate reductase; SPTR: 2,5-didehydrogluconate reductase; PFAM: Aldo/keto reductase family. | 0.524 |
| ADU47433.1 | ADU47747.1 | Intca_0906 | Intca_1229 | Peroxiredoxin, OsmC subfamily; COGs: COG1764 redox protein regulator of disulfide bond formation; InterPro IPR003718: IPR019904; KEGG: nca:Noca_1377 OsmC family protein; PFAM: OsmC family protein; SPTR: Putative ATP/GTP-binding protein; TIGRFAM: peroxiredoxin, OsmC subfamily; PFAM: OsmC-like protein; TIGRFAM: peroxiredoxin, OsmC subfamily. | COGs: COG0656 Aldo/keto reductase related to diketogulonate reductase; InterPro IPR001395: IPR018170: IPR020471; KEGG: tcu:Tcur_1587 2,5-didehydrogluconate reductase; PFAM: aldo/keto reductase; PRIAM: 2,5-didehydrogluconate reductase; SPTR: 2,5-didehydrogluconate reductase; PFAM: Aldo/keto reductase family. | 0.560 |
| ADU47433.1 | ADU49405.1 | Intca_0906 | Intca_2910 | Peroxiredoxin, OsmC subfamily; COGs: COG1764 redox protein regulator of disulfide bond formation; InterPro IPR003718: IPR019904; KEGG: nca:Noca_1377 OsmC family protein; PFAM: OsmC family protein; SPTR: Putative ATP/GTP-binding protein; TIGRFAM: peroxiredoxin, OsmC subfamily; PFAM: OsmC-like protein; TIGRFAM: peroxiredoxin, OsmC subfamily. | Trehalose-phosphatase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose. | 0.498 |
| ADU47746.1 | ADU47747.1 | Intca_1228 | Intca_1229 | Biotin carboxyl carrier protein; COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterProIPR005481: IPR005479: IPR005482: IPR000089: IPR 001882: IPR011761: IPR011764; KEGG: kse:Ksed_08190 acetyl/propionyl-CoA carboxylase, alpha subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; biotin/lipoyl attachment domain-containing protein; SPTR: Putative acyl-CoA carboxylase, alpha subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; Biotin carboxylase C-te [...] | COGs: COG0656 Aldo/keto reductase related to diketogulonate reductase; InterPro IPR001395: IPR018170: IPR020471; KEGG: tcu:Tcur_1587 2,5-didehydrogluconate reductase; PFAM: aldo/keto reductase; PRIAM: 2,5-didehydrogluconate reductase; SPTR: 2,5-didehydrogluconate reductase; PFAM: Aldo/keto reductase family. | 0.578 |
| ADU47746.1 | ADU47748.1 | Intca_1228 | Intca_1230 | Biotin carboxyl carrier protein; COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterProIPR005481: IPR005479: IPR005482: IPR000089: IPR 001882: IPR011761: IPR011764; KEGG: kse:Ksed_08190 acetyl/propionyl-CoA carboxylase, alpha subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; biotin/lipoyl attachment domain-containing protein; SPTR: Putative acyl-CoA carboxylase, alpha subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; Biotin carboxylase C-te [...] | KEGG: mlu:Mlut_01340 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.420 |
| ADU47747.1 | ADU46669.1 | Intca_1229 | Intca_0108 | COGs: COG0656 Aldo/keto reductase related to diketogulonate reductase; InterPro IPR001395: IPR018170: IPR020471; KEGG: tcu:Tcur_1587 2,5-didehydrogluconate reductase; PFAM: aldo/keto reductase; PRIAM: 2,5-didehydrogluconate reductase; SPTR: 2,5-didehydrogluconate reductase; PFAM: Aldo/keto reductase family. | COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR001395; KEGG: kfl:Kfla_0935 aldo/keto reductase; PFAM: aldo/keto reductase; SPTR: Aldo/keto reductase; PFAM: Aldo/keto reductase family. | 0.524 |
| ADU47747.1 | ADU47433.1 | Intca_1229 | Intca_0906 | COGs: COG0656 Aldo/keto reductase related to diketogulonate reductase; InterPro IPR001395: IPR018170: IPR020471; KEGG: tcu:Tcur_1587 2,5-didehydrogluconate reductase; PFAM: aldo/keto reductase; PRIAM: 2,5-didehydrogluconate reductase; SPTR: 2,5-didehydrogluconate reductase; PFAM: Aldo/keto reductase family. | Peroxiredoxin, OsmC subfamily; COGs: COG1764 redox protein regulator of disulfide bond formation; InterPro IPR003718: IPR019904; KEGG: nca:Noca_1377 OsmC family protein; PFAM: OsmC family protein; SPTR: Putative ATP/GTP-binding protein; TIGRFAM: peroxiredoxin, OsmC subfamily; PFAM: OsmC-like protein; TIGRFAM: peroxiredoxin, OsmC subfamily. | 0.560 |
| ADU47747.1 | ADU47746.1 | Intca_1229 | Intca_1228 | COGs: COG0656 Aldo/keto reductase related to diketogulonate reductase; InterPro IPR001395: IPR018170: IPR020471; KEGG: tcu:Tcur_1587 2,5-didehydrogluconate reductase; PFAM: aldo/keto reductase; PRIAM: 2,5-didehydrogluconate reductase; SPTR: 2,5-didehydrogluconate reductase; PFAM: Aldo/keto reductase family. | Biotin carboxyl carrier protein; COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterProIPR005481: IPR005479: IPR005482: IPR000089: IPR 001882: IPR011761: IPR011764; KEGG: kse:Ksed_08190 acetyl/propionyl-CoA carboxylase, alpha subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; biotin/lipoyl attachment domain-containing protein; SPTR: Putative acyl-CoA carboxylase, alpha subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; Biotin carboxylase C-te [...] | 0.578 |
| ADU47747.1 | ADU47748.1 | Intca_1229 | Intca_1230 | COGs: COG0656 Aldo/keto reductase related to diketogulonate reductase; InterPro IPR001395: IPR018170: IPR020471; KEGG: tcu:Tcur_1587 2,5-didehydrogluconate reductase; PFAM: aldo/keto reductase; PRIAM: 2,5-didehydrogluconate reductase; SPTR: 2,5-didehydrogluconate reductase; PFAM: Aldo/keto reductase family. | KEGG: mlu:Mlut_01340 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.598 |
| ADU47747.1 | ADU47982.1 | Intca_1229 | Intca_1467 | COGs: COG0656 Aldo/keto reductase related to diketogulonate reductase; InterPro IPR001395: IPR018170: IPR020471; KEGG: tcu:Tcur_1587 2,5-didehydrogluconate reductase; PFAM: aldo/keto reductase; PRIAM: 2,5-didehydrogluconate reductase; SPTR: 2,5-didehydrogluconate reductase; PFAM: Aldo/keto reductase family. | COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR001395; KEGG: ske:Sked_15540 predicted oxidoreductase, aryl-alcohol dehydrogenase like protein; PFAM: aldo/keto reductase; SPTR: K+ channel beta subunit; PFAM: Aldo/keto reductase family. | 0.515 |
| ADU47747.1 | ADU48259.1 | Intca_1229 | Intca_1746 | COGs: COG0656 Aldo/keto reductase related to diketogulonate reductase; InterPro IPR001395: IPR018170: IPR020471; KEGG: tcu:Tcur_1587 2,5-didehydrogluconate reductase; PFAM: aldo/keto reductase; PRIAM: 2,5-didehydrogluconate reductase; SPTR: 2,5-didehydrogluconate reductase; PFAM: Aldo/keto reductase family. | COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR020471: IPR018170: IPR001395; KEGG: nca:Noca_2622 aldo/keto reductase; PFAM: aldo/keto reductase; SPTR: Aldo/keto reductase; manually curated; PFAM: Aldo/keto reductase family. | 0.648 |
| ADU47747.1 | ADU48268.1 | Intca_1229 | Intca_1755 | COGs: COG0656 Aldo/keto reductase related to diketogulonate reductase; InterPro IPR001395: IPR018170: IPR020471; KEGG: tcu:Tcur_1587 2,5-didehydrogluconate reductase; PFAM: aldo/keto reductase; PRIAM: 2,5-didehydrogluconate reductase; SPTR: 2,5-didehydrogluconate reductase; PFAM: Aldo/keto reductase family. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.852 |
| ADU47747.1 | ADU48899.1 | Intca_1229 | Intca_2392 | COGs: COG0656 Aldo/keto reductase related to diketogulonate reductase; InterPro IPR001395: IPR018170: IPR020471; KEGG: tcu:Tcur_1587 2,5-didehydrogluconate reductase; PFAM: aldo/keto reductase; PRIAM: 2,5-didehydrogluconate reductase; SPTR: 2,5-didehydrogluconate reductase; PFAM: Aldo/keto reductase family. | COGs: COG2025 Electron transfer flavoprotein alpha subunit; InterPro IPR001308: IPR018206: IPR014730: IPR014731; KEGG: kse:Ksed_09610 electron transfer flavoprotein, alpha subunit; PFAM: Electron transfer flavoprotein alpha subunit; Electron transfer flavoprotein alpha/beta-subunit; SPTR: Putative electron transfer flavoprotein, alpha subunit; PFAM: Electron transfer flavoprotein domain; Electron transfer flavoprotein FAD-binding domain. | 0.512 |
| ADU47747.1 | ADU49214.1 | Intca_1229 | Intca_2713 | COGs: COG0656 Aldo/keto reductase related to diketogulonate reductase; InterPro IPR001395: IPR018170: IPR020471; KEGG: tcu:Tcur_1587 2,5-didehydrogluconate reductase; PFAM: aldo/keto reductase; PRIAM: 2,5-didehydrogluconate reductase; SPTR: 2,5-didehydrogluconate reductase; PFAM: Aldo/keto reductase family. | COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR001395; KEGG: kfl:Kfla_3500 aldo/keto reductase; PFAM: aldo/keto reductase; SPTR: Aldo/keto reductase; PFAM: Aldo/keto reductase family. | 0.515 |
| ADU47747.1 | ADU49405.1 | Intca_1229 | Intca_2910 | COGs: COG0656 Aldo/keto reductase related to diketogulonate reductase; InterPro IPR001395: IPR018170: IPR020471; KEGG: tcu:Tcur_1587 2,5-didehydrogluconate reductase; PFAM: aldo/keto reductase; PRIAM: 2,5-didehydrogluconate reductase; SPTR: 2,5-didehydrogluconate reductase; PFAM: Aldo/keto reductase family. | Trehalose-phosphatase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose. | 0.704 |
| ADU47748.1 | ADU47746.1 | Intca_1230 | Intca_1228 | KEGG: mlu:Mlut_01340 hypothetical protein; SPTR: Putative uncharacterized protein. | Biotin carboxyl carrier protein; COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterProIPR005481: IPR005479: IPR005482: IPR000089: IPR 001882: IPR011761: IPR011764; KEGG: kse:Ksed_08190 acetyl/propionyl-CoA carboxylase, alpha subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; biotin/lipoyl attachment domain-containing protein; SPTR: Putative acyl-CoA carboxylase, alpha subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; Biotin carboxylase C-te [...] | 0.420 |
| ADU47748.1 | ADU47747.1 | Intca_1230 | Intca_1229 | KEGG: mlu:Mlut_01340 hypothetical protein; SPTR: Putative uncharacterized protein. | COGs: COG0656 Aldo/keto reductase related to diketogulonate reductase; InterPro IPR001395: IPR018170: IPR020471; KEGG: tcu:Tcur_1587 2,5-didehydrogluconate reductase; PFAM: aldo/keto reductase; PRIAM: 2,5-didehydrogluconate reductase; SPTR: 2,5-didehydrogluconate reductase; PFAM: Aldo/keto reductase family. | 0.598 |
| ADU47982.1 | ADU47747.1 | Intca_1467 | Intca_1229 | COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR001395; KEGG: ske:Sked_15540 predicted oxidoreductase, aryl-alcohol dehydrogenase like protein; PFAM: aldo/keto reductase; SPTR: K+ channel beta subunit; PFAM: Aldo/keto reductase family. | COGs: COG0656 Aldo/keto reductase related to diketogulonate reductase; InterPro IPR001395: IPR018170: IPR020471; KEGG: tcu:Tcur_1587 2,5-didehydrogluconate reductase; PFAM: aldo/keto reductase; PRIAM: 2,5-didehydrogluconate reductase; SPTR: 2,5-didehydrogluconate reductase; PFAM: Aldo/keto reductase family. | 0.515 |
| ADU48259.1 | ADU47747.1 | Intca_1746 | Intca_1229 | COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR020471: IPR018170: IPR001395; KEGG: nca:Noca_2622 aldo/keto reductase; PFAM: aldo/keto reductase; SPTR: Aldo/keto reductase; manually curated; PFAM: Aldo/keto reductase family. | COGs: COG0656 Aldo/keto reductase related to diketogulonate reductase; InterPro IPR001395: IPR018170: IPR020471; KEGG: tcu:Tcur_1587 2,5-didehydrogluconate reductase; PFAM: aldo/keto reductase; PRIAM: 2,5-didehydrogluconate reductase; SPTR: 2,5-didehydrogluconate reductase; PFAM: Aldo/keto reductase family. | 0.648 |
| ADU48268.1 | ADU47747.1 | Intca_1755 | Intca_1229 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | COGs: COG0656 Aldo/keto reductase related to diketogulonate reductase; InterPro IPR001395: IPR018170: IPR020471; KEGG: tcu:Tcur_1587 2,5-didehydrogluconate reductase; PFAM: aldo/keto reductase; PRIAM: 2,5-didehydrogluconate reductase; SPTR: 2,5-didehydrogluconate reductase; PFAM: Aldo/keto reductase family. | 0.852 |