| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADU47737.1 | ADU47755.1 | Intca_1219 | Intca_1237 | COGs: COG0572 Uridine kinase; KEGG: kse:Ksed_08140 uridine kinase; SPTR: Uridine kinase; PFAM: Phosphoribulokinase / Uridine kinase family. | Maf protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 0.902 |
| ADU47737.1 | ADU48120.1 | Intca_1219 | Intca_1607 | COGs: COG0572 Uridine kinase; KEGG: kse:Ksed_08140 uridine kinase; SPTR: Uridine kinase; PFAM: Phosphoribulokinase / Uridine kinase family. | COGs: COG0284 Orotidine-5'-phosphate decarboxylase; InterPro IPR018089: IPR001754: IPR011995; KEGG: kra:Krad_3000 orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; PRIAM: Orotidine-5'-phosphate decarboxylase; SPTR: Orotidine 5'-phosphate decarboxylase; TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: orotidine 5'-phosphate decarboxylase, subfamily 2; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.910 |
| ADU47737.1 | ADU48453.1 | Intca_1219 | Intca_1942 | COGs: COG0572 Uridine kinase; KEGG: kse:Ksed_08140 uridine kinase; SPTR: Uridine kinase; PFAM: Phosphoribulokinase / Uridine kinase family. | COGs: COG1435 Thymidine kinase; InterPro IPR001267: IPR020634; KEGG: kse:Ksed_15850 thymidine kinase; PFAM: thymidine kinase; PRIAM: Thymidine kinase; SPTR: Thymidine kinase; PFAM: Thymidine kinase. | 0.454 |
| ADU47737.1 | cmk | Intca_1219 | Intca_1835 | COGs: COG0572 Uridine kinase; KEGG: kse:Ksed_08140 uridine kinase; SPTR: Uridine kinase; PFAM: Phosphoribulokinase / Uridine kinase family. | COGs: COG0283 Cytidylate kinase; InterPro IPR003136: IPR011994; KEGG: ske:Sked_19860 cytidylate kinase; PFAM: cytidylate kinase region; SPTR: Cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: Cytidylate kinase; TIGRFAM: cytidylate kinase. | 0.924 |
| ADU47737.1 | pyrR | Intca_1219 | Intca_1600 | COGs: COG0572 Uridine kinase; KEGG: kse:Ksed_08140 uridine kinase; SPTR: Uridine kinase; PFAM: Phosphoribulokinase / Uridine kinase family. | Uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. | 0.911 |
| ADU47737.1 | upp | Intca_1219 | Intca_0397 | COGs: COG0572 Uridine kinase; KEGG: kse:Ksed_08140 uridine kinase; SPTR: Uridine kinase; PFAM: Phosphoribulokinase / Uridine kinase family. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.985 |
| ADU47755.1 | ADU47737.1 | Intca_1237 | Intca_1219 | Maf protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | COGs: COG0572 Uridine kinase; KEGG: kse:Ksed_08140 uridine kinase; SPTR: Uridine kinase; PFAM: Phosphoribulokinase / Uridine kinase family. | 0.902 |
| ADU47755.1 | ADU48120.1 | Intca_1237 | Intca_1607 | Maf protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | COGs: COG0284 Orotidine-5'-phosphate decarboxylase; InterPro IPR018089: IPR001754: IPR011995; KEGG: kra:Krad_3000 orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; PRIAM: Orotidine-5'-phosphate decarboxylase; SPTR: Orotidine 5'-phosphate decarboxylase; TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: orotidine 5'-phosphate decarboxylase, subfamily 2; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.916 |
| ADU47755.1 | ADU48453.1 | Intca_1237 | Intca_1942 | Maf protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | COGs: COG1435 Thymidine kinase; InterPro IPR001267: IPR020634; KEGG: kse:Ksed_15850 thymidine kinase; PFAM: thymidine kinase; PRIAM: Thymidine kinase; SPTR: Thymidine kinase; PFAM: Thymidine kinase. | 0.900 |
| ADU47755.1 | cmk | Intca_1237 | Intca_1835 | Maf protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | COGs: COG0283 Cytidylate kinase; InterPro IPR003136: IPR011994; KEGG: ske:Sked_19860 cytidylate kinase; PFAM: cytidylate kinase region; SPTR: Cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: Cytidylate kinase; TIGRFAM: cytidylate kinase. | 0.923 |
| ADU47755.1 | ndk | Intca_1237 | Intca_2209 | Maf protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.911 |
| ADU47755.1 | pyrG | Intca_1237 | Intca_1574 | Maf protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.908 |
| ADU47755.1 | pyrR | Intca_1237 | Intca_1600 | Maf protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. | 0.916 |
| ADU47755.1 | thyA | Intca_1237 | Intca_2185 | Maf protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.900 |
| ADU47755.1 | tmk | Intca_1237 | Intca_0572 | Maf protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.907 |
| ADU47755.1 | upp | Intca_1237 | Intca_0397 | Maf protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.900 |
| ADU48120.1 | ADU47737.1 | Intca_1607 | Intca_1219 | COGs: COG0284 Orotidine-5'-phosphate decarboxylase; InterPro IPR018089: IPR001754: IPR011995; KEGG: kra:Krad_3000 orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; PRIAM: Orotidine-5'-phosphate decarboxylase; SPTR: Orotidine 5'-phosphate decarboxylase; TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: orotidine 5'-phosphate decarboxylase, subfamily 2; Belongs to the OMP decarboxylase family. Type 2 subfamily. | COGs: COG0572 Uridine kinase; KEGG: kse:Ksed_08140 uridine kinase; SPTR: Uridine kinase; PFAM: Phosphoribulokinase / Uridine kinase family. | 0.910 |
| ADU48120.1 | ADU47755.1 | Intca_1607 | Intca_1237 | COGs: COG0284 Orotidine-5'-phosphate decarboxylase; InterPro IPR018089: IPR001754: IPR011995; KEGG: kra:Krad_3000 orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; PRIAM: Orotidine-5'-phosphate decarboxylase; SPTR: Orotidine 5'-phosphate decarboxylase; TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: orotidine 5'-phosphate decarboxylase, subfamily 2; Belongs to the OMP decarboxylase family. Type 2 subfamily. | Maf protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 0.916 |
| ADU48120.1 | cmk | Intca_1607 | Intca_1835 | COGs: COG0284 Orotidine-5'-phosphate decarboxylase; InterPro IPR018089: IPR001754: IPR011995; KEGG: kra:Krad_3000 orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; PRIAM: Orotidine-5'-phosphate decarboxylase; SPTR: Orotidine 5'-phosphate decarboxylase; TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: orotidine 5'-phosphate decarboxylase, subfamily 2; Belongs to the OMP decarboxylase family. Type 2 subfamily. | COGs: COG0283 Cytidylate kinase; InterPro IPR003136: IPR011994; KEGG: ske:Sked_19860 cytidylate kinase; PFAM: cytidylate kinase region; SPTR: Cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: Cytidylate kinase; TIGRFAM: cytidylate kinase. | 0.648 |
| ADU48120.1 | pyrG | Intca_1607 | Intca_1574 | COGs: COG0284 Orotidine-5'-phosphate decarboxylase; InterPro IPR018089: IPR001754: IPR011995; KEGG: kra:Krad_3000 orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; PRIAM: Orotidine-5'-phosphate decarboxylase; SPTR: Orotidine 5'-phosphate decarboxylase; TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: orotidine 5'-phosphate decarboxylase, subfamily 2; Belongs to the OMP decarboxylase family. Type 2 subfamily. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.443 |