Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
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gene neighborhood
gene co-occurrence
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ADU47803.1FHA domain containing protein; COGs: COG1674 DNA segregation ATPase FtsK/SpoIIIE and related protein; InterPro IPR019793: IPR000253: IPR002543: IPR003593; KEGG: tcu:Tcur_4147 cell divisionFtsK/SpoIIIE; PFAM: cell divisionFtsK/SpoIIIE; Forkhead-associated protein; SMART: Forkhead-associated protein; AAA ATPase; SPTR: Cell divisionFtsK/SpoIIIE; PFAM: FtsK/SpoIIIE family; FHA domain. (1482 aa)    
Predicted Functional Partners:
ADU48984.1
COGs: COG0567 2-oxoglutarate dehydrogenase complex dehydrogenase (E1); InterProIPR011603: IPR001078: IPR001017: IPR005475: IPR 000897; KEGG: kra:Krad_1228 alpha-ketoglutarate decarboxylase; PFAM: Transketolase central region; dehydrogenase E1 component; catalytic domain-containing protein of components of various dehydrogenase complexes; SPTR: Alpha-ketoglutarate decarboxylase; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); Dehydrogenase E1 component; Transketolase, pyrimidine binding domain; TIGRFAM: 2-oxoglutarate [...]
   
 
 0.945
ADU46624.1
COGs: COG0515 Serine/threonine protein kinase; InterProIPR017442: IPR005543: IPR020635: IPR002290: IPR 017441: IPR008271: IPR000719; KEGG: kra:Krad_0072 protein kinase; PFAM: Serine/threonine-protein kinase-like domain; PASTA domain containing protein; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domain; PASTA domain containing protein; SPTR: Tyrosine protein kinase:Serine/threonine protein kinase:PASTA; PFAM: Protein kinase domain; PASTA domain.
   
 
 0.920
ADU47757.1
COGs: COG0515 Serine/threonine protein kinase; InterProIPR017442: IPR005543: IPR008271: IPR000719: IPR 020635: IPR002290; KEGG: bcv:Bcav_1908 serine/threonine protein kinase with PASTA sensor(s); PFAM: Serine/threonine-protein kinase-like domain; PASTA domain containing protein; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domain; PASTA domain containing protein; SPTR: Serine/threonine protein kinase with PASTA sensor(S); PFAM: Protein kinase domain.
   
 
 0.920
ADU48474.1
COGs: COG0515 Serine/threonine protein kinase; InterProIPR017442: IPR005543: IPR020635: IPR002290: IPR 008271: IPR000719; KEGG: nca:Noca_3086 protein kinase; PFAM: Serine/threonine-protein kinase-like domain; PASTA domain containing protein; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domain; PASTA domain containing protein; SPTR: Serine/threonine kinase; PFAM: Protein kinase domain; PASTA domain.
   
 
 0.920
ADU49355.1
KEGG: cms:CMS_2757 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Proteins of 100 residues with WXG; Belongs to the WXG100 family.
 
 
 0.854
ADU47942.1
ComEC/Rec2-related protein; COGs: COG2333 hydrolase (metallo-beta-lactamase superfamily); InterPro IPR004477; KEGG: kra:Krad_3434 DNA internalization-related competence protein ComEC/Rec2; PFAM: ComEC/Rec2-related protein; SPTR: Putative integral membrane protein; TIGRFAM: ComEC/Rec2-related protein; PFAM: Competence protein; Metallo-beta-lactamase superfamily; TIGRFAM: ComEC/Rec2-related protein; DNA internalization-related competence protein ComEC/Rec2.
  
  
 0.601
ribA-2
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the GTP cyclohydrolase II family.
  
  
 0.583
ADU49596.1
Hypothetical protein; COGs: COG3451 Type IV secretory pathway VirB4 protein; KEGG: mlu:Mlut_00150 hypothetical protein; SPTR: Putative uncharacterized protein.
  
  
 0.557
ADU49309.1
Response regulator receiver protein; COGs: COG0492 Thioredoxin reductase; InterPro IPR001789: IPR000103: IPR013027; KEGG: rer:RER_40230 two-component system thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver modulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Response regulator receiver domain.
  
  
 0.554
ADU48035.1
Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein.
  
 
 0.548
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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