Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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ADU47815.1Peptidase M23; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047; KEGG: cfl:Cfla_1246 peptidase M23; PFAM: Peptidase M23; SPTR: Putative uncharacterized protein; PFAM: Peptidase family M23. (471 aa)    
Predicted Functional Partners:
ADU47814.1
Protein of unknown function DUF214; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
 
  
 0.791
ftsE
Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division.
 
   
 0.682
ADU47016.1
Peptidoglycan glycosyltransferase; COGs: COG0744 Membrane carboxypeptidase (penicillin-binding protein); InterPro IPR001264: IPR001460; KEGG: kse:Ksed_25450 membrane carboxypeptidase (penicillin-binding protein); PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Putative transpeptidase; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase.
  
   
 0.640
smpB
SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]
       0.627
ADU47817.1
InterPro IPR018702; KEGG: bcv:Bcav_2765 hypothetical protein; PFAM: Protein of unknown function DUF2207, membrane; SPTR: Putative uncharacterized protein; PFAM: Predicted membrane protein (DUF2207).
  
    0.503
ADU50092.1
Peptidoglycan glycosyltransferase; COGs: COG0744 Membrane carboxypeptidase (penicillin-binding protein); InterPro IPR001264: IPR001460; KEGG: kra:Krad_4341 glycosyl transferase family 51; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Putative secreted penicillin-binding protein; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase.
  
   
 0.477
ADU47777.1
Hypothetical protein; KEGG: tmt:Tmath_0720 capsule polysaccharide biosynthesis protein; SPTR: Putative uncharacterized protein; PFAM: Capsule polysaccharide biosynthesis protein.
  
     0.450
prfB
Bacterial peptide chain release factor 2 (bRF-2); Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
  
  
 0.450
ADU46689.1
COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR007887: IPR001460: IPR002137; KEGG: nca:Noca_4600 penicillin-binding protein, transpeptidase; PFAM: penicillin-binding protein transpeptidase; NTF2 domain protein transpeptidase; SPTR: Penicillin-binding protein, transpeptidase; PFAM: Penicillin binding protein transpeptidase domain; NTF2-like N-terminal transpeptidase domain; Penicillin-binding Protein dimerisation domain.
 
   
 0.434
ADU47776.1
Polysaccharide biosynthesis protein; InterPro IPR000812: IPR002797; KEGG: cwo:Cwoe_0093 polysaccharide biosynthesis protein; PFAM: polysaccharide biosynthesis protein; SPTR: Polysaccharide biosynthesis protein; PFAM: Polysaccharide biosynthesis protein.
  
     0.423
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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