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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU47820.1Thioredoxin; COGs: COG3118 Thioredoxin domain-containing protein; InterProIPR005746: IPR006662: IPR017937: IPR013766: IPR 017936; KEGG: ske:Sked_24970 thioredoxin; PFAM: Thioredoxin domain-containing protein; SPTR: Thioredoxin; TIGRFAM: thioredoxin; PFAM: Thioredoxin; TIGRFAM: thioredoxin; Belongs to the thioredoxin family. (129 aa)    
Predicted Functional Partners:
ADU49309.1
Response regulator receiver protein; COGs: COG0492 Thioredoxin reductase; InterPro IPR001789: IPR000103: IPR013027; KEGG: rer:RER_40230 two-component system thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver modulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Response regulator receiver domain.
  
 
 0.877
ADU50110.1
COGs: COG0492 Thioredoxin reductase; InterPro IPR013027: IPR000103: IPR005982: IPR008255; KEGG: kse:Ksed_26940 thioredoxin-disulfide reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Thioredoxin reductase; TIGRFAM: thioredoxin reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase.
 
 
 0.721
ADU47821.1
Protein of unknown function DUF541; COGs: COG2968 conserved hypothetical protein; InterPro IPR007497; KEGG: tpr:Tpau_2768 protein of unknown function DUF541; PFAM: protein of unknown function DUF541; SPTR: Outer membrane protein, 28kDa; PFAM: Protein of unknown function (DUF541).
       0.605
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 
 0.551
groS
Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
 
 
 0.491
ADU46749.1
Pyridine nucleotide-disulfide oxidoreductase dimerization region; COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterPro IPR001327: IPR004099: IPR013027: IPR000815; KEGG: sco:SCO3443 pyridine nucleotide-disulphide oxidoreductase; PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Putative pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain.
  
 
 0.489
ADU49856.1
Manganese/iron superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
   
 
 0.487
ADU49060.1
COGs: COG0695 Glutaredoxin and related protein; InterPro IPR002109: IPR011915: IPR017937; KEGG: bcv:Bcav_2898 glutaredoxin-like protein; PFAM: glutaredoxin; SPTR: Glutaredoxin-like protein; TIGRFAM: glutaredoxin-like protein; PFAM: Glutaredoxin; TIGRFAM: Glutaredoxin-like protein.
  
  
 0.460
ADU47822.1
VanZ family protein; InterPro IPR006976; KEGG: mlu:Mlut_19790 hypothetical protein; PFAM: VanZ family protein; SPTR: Putative uncharacterized protein; PFAM: VanZ like family.
       0.449
groL
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
 
 0.448
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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