STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU47824.1Protein of unknown function DUF179; COGs: COG1678 Putative transcriptional regulator protein; InterPro IPR003774; KEGG: kra:Krad_3774 hypothetical protein; PFAM: protein of unknown function DUF179; SPTR: UPF0301 protein Krad_3774; PFAM: Uncharacterized ACR, COG1678. (186 aa)    
Predicted Functional Partners:
ADU47957.1
Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
  
 0.993
ADU47826.1
KEGG: aau:AAur_2578 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3039).
       0.827
ADU47825.1
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
       0.788
ADU48101.1
Holliday junction resolvase YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.
  
  
 0.782
ADU46822.1
NHL repeat containing protein; InterPro IPR000866: IPR001258: IPR017936; KEGG: ach:Achl_3716 NHL repeat containing protein; PFAM: NHL repeat containing protein; alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; SPTR: NHL repeat containing protein; PFAM: NHL repeat; AhpC/TSA family.
   
 
 0.774
ADU47210.1
Redoxin domain protein; InterPro IPR017909: IPR017936: IPR013740; KEGG: kse:Ksed_24350 thiol-disulfide isomerase-like thioredoxin; PFAM: Redoxin domain protein; SPTR: Putative uncharacterized protein; PFAM: Redoxin.
   
 
 0.774
ADU46564.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 
 0.734
ADU48766.1
KEGG: cmi:CMM_1413 hypothetical protein; SPTR: Putative uncharacterized protein.
   
    0.718
ADU47823.1
DEAD/DEAH box helicase domain protein; COGs: COG0513 Superfamily II DNA and RNA helicase; InterProIPR011545: IPR001650: IPR014001: IPR014021: IPR 014014; KEGG: kse:Ksed_10490 DNA/RNA helicase, superfamily II; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: ATP-dependent RNA helicase; manually curated; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase.
   
   0.714
ADU46779.1
Transcriptional regulator, GntR family; COGs: COG1725 transcriptional regulator protein; InterPro IPR000524; KEGG: nfa:nfa49100 putative transcriptional regulator; PFAM: regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: Putative transcriptional regulator; PFAM: Bacterial regulatory proteins, gntR family.
   
    0.700
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.