STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU47830.1COGs: COG3185 4-hydroxyphenylpyruvate dioxygenase and related hemolysins; InterPro IPR005956: IPR004360; KEGG: rha:RHA1_ro03170 4-hydroxyphenylpyruvate dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; PRIAM: 4-hydroxyphenylpyruvate dioxygenase; SPTR: Putative 4-hydroxyphenylpyruvate dioxygenase; TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase. (410 aa)    
Predicted Functional Partners:
ADU47835.1
COGs: COG3508 Homogentisate 1 2-dioxygenase; InterPro IPR005708; KEGG: kse:Ksed_10650 homogentisate 1,2-dioxygenase; PFAM: homogentisate 12-dioxygenase; SPTR: Putative dioxygenase; PFAM: homogentisate 1,2-dioxygenase; TIGRFAM: homogentisate 1,2-dioxygenase.
 
 0.998
ADU46698.1
Carbamoyl-phosphate synthase L chain ATP-binding protein; COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterProIPR005481: IPR005479: IPR005482: IPR000089: IPR 000022: IPR011761: IPR011764: IPR011763; KEGG: kfl:Kfla_3307 carbamoyl-phosphate synthase L chain ATP-binding protein; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; biotin/lipoyl attachment domain-containing protein; carboxyl transferase; SPTR: Carbamoyl-phosphate synthase L chain ATP-binding protein; PFAM: Car [...]
  
 
 0.931
pat
Histidinol-phosphate aminotransferase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
    
 0.918
hisC
COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR005861: IPR001917: IPR004839; KEGG: sna:Snas_3996 histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; SPTR: Histidinol-phosphate aminotransferase; TIGRFAM: histidinol-phosphate aminotransferase; PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
    
 0.911
ADU49702.1
FAD dependent oxidoreductase; COGs: COG0665 Glycine/D-amino acid oxidase (deaminating); InterPro IPR006076; KEGG: kfl:Kfla_2551 D-amino-acid dehydrogenase; PFAM: FAD dependent oxidoreductase; SPTR: D-amino-acid dehydrogenase; PFAM: FAD dependent oxidoreductase.
   
 
 0.911
ADU47833.1
Fumarylacetoacetate hydrolase; COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR005959: IPR015377: IPR002529; KEGG: kse:Ksed_10630 fumarylacetoacetate hydrolase; PFAM: Domain of unknown function DUF1969; fumarylacetoacetate (FAA) hydrolase; PRIAM: Fumarylacetoacetase; SPTR: Putative fumarylacetoacetase; TIGRFAM: fumarylacetoacetase; PFAM: Domain of unknown function (DUF1969); Fumarylacetoacetate (FAA) hydrolase family; TIGRFAM: fumarylacetoacetase.
 
  
 0.895
ADU49329.1
Amidase; COGs: COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidase; InterPro IPR000120: IPR020556; KEGG: rop:ROP_37880 putative amidase; PFAM: Amidase; SPTR: Putative amidase; PFAM: Amidase; Belongs to the amidase family.
  
 
  0.820
ADU49556.1
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR017896: IPR011895: IPR002880: IPR019752: IPR 019456: IPR011766: IPR017900; KEGG: mmi:MMAR_3408 pyruvate ferredoxin/flavodoxin oxidoreductase family protein; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Pyruvate ferredoxin/flavodoxin oxidoreductase family protein; TIGRFAM [...]
     
 0.702
ADU47829.1
Transcriptional regulator, AsnC family; COGs: COG1522 Transcriptional regulators; InterPro IPR019887: IPR019888; KEGG: cai:Caci_1485 transcriptional regulator, AsnC family; PFAM: Transcription regulator AsnC-type-like; SMART: Transcription regulator AsnC-type; SPTR: Putative asnC-family transcriptional regulator; PFAM: AsnC family.
 
     0.697
ADU47753.1
COGs: COG4799 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR000022: IPR011762: IPR011763; KEGG: kse:Ksed_08220 acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta); PFAM: carboxyl transferase; SPTR: YngE; PFAM: Carboxyl transferase domain.
  
  
 0.619
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.