STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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[Homology]
Score
ADU47870.1Thioesterase superfamily protein; COGs: COG0824 thioesterase; InterPro IPR006683; KEGG: kse:Ksed_08950 predicted thioesterase; PFAM: thioesterase superfamily protein; SPTR: Putative uncharacterized protein; PFAM: Thioesterase superfamily. (156 aa)    
Predicted Functional Partners:
ADU47871.1
KEGG: kse:Ksed_08960 hypothetical protein; SPTR: Putative uncharacterized protein.
 
    0.889
ADU48573.1
COGs: COG0331 (acyl-carrier-protein) S-malonyltransferase; InterPro IPR014043; KEGG: ach:Achl_2205 putative (acyl-carrier-protein) S-malonyltransferase; PFAM: Acyl transferase; PRIAM: [Acyl-carrier-protein] S-malonyltransferase; SPTR: Acyl-carrier-protein S-malonyltransferase; PFAM: Acyl transferase domain.
 
  
 0.681
ADU47868.1
Choloyl-CoA hydrolase; COGs: COG1946 Acyl-CoA thioesterase; InterPro IPR003703; KEGG: aau:AAur_2394 acyl-CoA thioesterase II; PFAM: acyl-CoA thioesterase; PRIAM: Choloyl-CoA hydrolase; SPTR: Acyl-CoA thioesterase II; PFAM: Acyl-CoA thioesterase; TIGRFAM: acyl-CoA thioesterase II.
     
 0.667
acpP
Phosphopantetheine-binding protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
 
 
 0.629
ADU49296.1
MaoC domain protein dehydratase; COGs: COG2030 Acyl dehydratase; InterPro IPR002539; KEGG: sco:SCO4637 hypothetical protein; PFAM: MaoC domain protein dehydratase; SPTR: Putative uncharacterized protein; PFAM: MaoC like domain.
 
   
 0.575
ADU49297.1
Hypothetical protein; InterPro IPR016709; KEGG: aau:AAur_3002 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: MaoC like domain; Belongs to the UPF0336 family.
 
   
 0.570
ADU47869.1
ATP-dependent DNA helicase, RecQ family; COGs: COG0514 Superfamily II DNA helicase; InterProIPR018329: IPR002464: IPR011545: IPR001650: IPR 014001: IPR014021; KEGG: kse:Ksed_06850 ATP-dependent DNA helicase RecQ; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: helicase domain protein; DEAD-like helicase; SPTR: ATP-dependent DNA helicase; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase, RecQ family.
       0.556
ADU48990.1
COGs: COG2902 NAD-specific glutamate dehydrogenase; InterPro IPR007780; KEGG: bcv:Bcav_1575 NAD-glutamate dehydrogenase; PFAM: NAD-glutamate dehydrogenase; SPTR: Putative uncharacterized protein; PFAM: Bacterial NAD-glutamate dehydrogenase.
  
    0.547
fabH
3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
 
 0.516
ADU48425.1
COGs: COG1250 3-hydroxyacyl-CoA dehydrogenase; InterPro IPR001753: IPR006176: IPR006108; KEGG: tcu:Tcur_1759 3-hydroxyacyl-CoA dehydrogenase NAD-binding protein; PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain-containing protein; SPTR: 3-hydroxyacyl-CoA dehydrogenase NAD-binding protein; PFAM: Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.
 
  
 0.484
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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