STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU47880.1Protein serine/threonine phosphatase; COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR018486: IPR010822: IPR001932; KEGG: nca:Noca_3481 stage II sporulation E family protein; PFAM: Stage II sporulation protein E; SMART: protein phosphatase 2C domain protein; SPTR: Putative integral membrane protein; PFAM: Stage II sporulation protein E (SpoIIE). (371 aa)    
Predicted Functional Partners:
ADU48933.1
InterPro IPR002645; KEGG: kra:Krad_1274 anti-sigma-factor antagonist; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; SPTR: Putative uncharacterized protein; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor.
 
 
 0.848
ADU49393.1
ATP-binding region ATPase domain protein; InterPro IPR003018: IPR003594: IPR018247; KEGG: cai:Caci_4163 putative PAS/PAC sensor protein; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; SPTR: PAS/PAC sensor hybrid histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
 
 0.814
ADU47303.1
Protein serine/threonine phosphatase; COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR001932: IPR007895: IPR010822: IPR003594; KEGG: gob:Gobs_0116 multi-sensor signal transduction histidine kinase; PFAM: Stage II sporulation protein E; MASE1 domain protein; ATP-binding region ATPase domain protein; SMART: protein phosphatase 2C domain protein; SPTR: Multi-sensor signal transduction histidine kinase; PFAM: Stage II sporulation protein E (SpoIIE); MASE1.
 
 
0.800
ADU47078.1
Anti-sigma-factor antagonist; COGs: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); InterPro IPR002645: IPR003658; KEGG: kfl:Kfla_0571 anti-sigma-factor antagonist; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; SPTR: Anti-sigma factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor; anti-sigma F factor antagonist.
 
 
 0.795
ADU49030.1
Metal dependent phosphohydrolase; COGs: COG2206 HD-GYP domain; InterPro IPR003607; KEGG: tfu:Tfu_0551 putative lipoprotein; SMART: metal-dependent phosphohydrolase HD region; SPTR: Putative lipoprotein.
 
    0.723
ADU47302.1
Anti-anti-sigma factor; InterPro IPR002645: IPR003658; KEGG: svi:Svir_34950 anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); PFAM: Sulfate transporter/antisigma-factor antagonist STAS; SPTR: Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor); TIGRFAM: anti-anti-sigma factor; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor; Belongs to the anti-sigma-factor antagonist family.
 
 
 0.705
ADU48064.1
PAS/PAC sensor signal transduction histidine kinase; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterProIPR000014: IPR003661: IPR003594: IPR005467: IPR 004358: IPR013656; KEGG: sco:SCO1596 two-component sensor; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: Two-component sensor; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoa [...]
 
     0.640
ADU46728.1
ATP-binding region ATPase domain protein; InterPro IPR003594; KEGG: tcu:Tcur_0095 putative anti-sigma regulatory factor, serine/threonine protein kinase; PFAM: ATP-binding region ATPase domain protein; SPTR: Putative regulatory protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
  
   
 0.639
ADU47637.1
Anti-sigma-factor antagonist; InterPro IPR002645; KEGG: gob:Gobs_2816 anti-sigma-factor antagonist; SPTR: Anti-sigma-factor antagonist.
  
 
 0.631
ADU47879.1
COGs: COG0698 Ribose 5-phosphate isomerase RpiB; InterPro IPR011860: IPR003500; KEGG: kse:Ksed_09040 ribose 5-phosphate isomerase; PFAM: Ribose/galactose isomerase; SPTR: Ribose 5-phosphate isomerase; TIGRFAM: ribose 5-phosphate isomerase; sugar-phosphate isomerase, RpiB/LacA/LacB family; PFAM: Ribose/Galactose Isomerase; TIGRFAM: ribose 5-phosphate isomerase; sugar-phosphate isomerases, RpiB/LacA/LacB family.
       0.629
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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