STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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[Homology]
Score
ADU47909.1COGs: COG4147 symporter; InterPro IPR001734; KEGG: sro:Sros_6322 SSS sodium solute transporter superfamily; PFAM: Na+/solute symporter; SPTR: SSS sodium solute transporter superfamily; PFAM: Sodium:solute symporter family; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (519 aa)    
Predicted Functional Partners:
ADU47910.1
Protein of unknown function DUF485; COGs: COG3162 membrane protein; InterPro IPR007436; KEGG: ske:Sked_13330 predicted membrane protein; PFAM: protein of unknown function DUF485; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function, DUF485.
 
  
 0.965
ADU47908.1
KEGG: tbi:Tbis_2132 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.953
ADU47907.1
Two component transcriptional regulator, LytTR family; COGs: COG3279 Response regulator of the LytR/AlgR family; InterPro IPR001789: IPR007492; KEGG: nca:Noca_0357 response regulator receiver; PFAM: response regulator receiver; LytTr DNA-binding region; SMART: response regulator receiver; SPTR: Response regulator receiver; PFAM: Response regulator receiver domain; LytTr DNA-binding domain.
 
     0.944
ADU47906.1
Signal transduction histidine kinase, LytS; COGs: COG3275 Putative regulator of cell autolysis; InterPro IPR010559: IPR003594; KEGG: nca:Noca_0358 histidine kinase internal region; PFAM: histidine kinase internal region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Histidine kinase internal region; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
     0.919
ADU47911.1
SSS sodium solute transporter superfamily; COGs: COG4147 symporter; InterPro IPR019900: IPR001734; KEGG: bcv:Bcav_3373 SSS sodium solute transporter superfamily; PFAM: Na+/solute symporter; SPTR: SSS sodium solute transporter superfamily; TIGRFAM: SSS sodium solute transporter superfamily; PFAM: Sodium:solute symporter family; TIGRFAM: transporter, SSS family; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
    
0.698
ADU49901.1
Putative CBS domain and cyclic nucleotide-regulated nucleotidyltransferase; COGs: COG2905 signal-transduction protein containing cAMP-binding and CBS domains; InterPro IPR000595: IPR000644: IPR005105: IPR018821; KEGG: tra:Trad_0246 putative CBS domain and cyclic nucleotide-regulated nucleotidyltransferase; PFAM: protein of unknown function DUF294 nucleotidyltransferase; CBS domain containing protein; cyclic nucleotide-binding; Domain of unknown function DUF294, putative nucleotidyltransferase substrate-binding; SMART: CBS domain containing protein; cyclic nucleotide-binding; SPTR: Puta [...]
 
    0.534
obg
GTP-binding protein Obg/CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
     
 0.468
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
  
 0.431
ADU49902.1
COGs: COG0847 DNA polymerase III epsilon subunit and related 3'-5' exonuclease; InterPro IPR013520: IPR006055; KEGG: mgm:Mmc1_1044 exonuclease, RNase T and DNA polymerase III; PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease; SPTR: Exonuclease RNase T and DNA polymerase III; PFAM: Exonuclease.
 
    0.403
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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