STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU47910.1Protein of unknown function DUF485; COGs: COG3162 membrane protein; InterPro IPR007436; KEGG: ske:Sked_13330 predicted membrane protein; PFAM: protein of unknown function DUF485; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function, DUF485. (111 aa)    
Predicted Functional Partners:
ADU47911.1
SSS sodium solute transporter superfamily; COGs: COG4147 symporter; InterPro IPR019900: IPR001734; KEGG: bcv:Bcav_3373 SSS sodium solute transporter superfamily; PFAM: Na+/solute symporter; SPTR: SSS sodium solute transporter superfamily; TIGRFAM: SSS sodium solute transporter superfamily; PFAM: Sodium:solute symporter family; TIGRFAM: transporter, SSS family; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
  
 0.995
ADU47909.1
COGs: COG4147 symporter; InterPro IPR001734; KEGG: sro:Sros_6322 SSS sodium solute transporter superfamily; PFAM: Na+/solute symporter; SPTR: SSS sodium solute transporter superfamily; PFAM: Sodium:solute symporter family; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
  
 0.957
ADU47357.1
COGs: COG2225 Malate synthase; InterPro IPR011076: IPR006252: IPR019830; KEGG: kfl:Kfla_0722 malate synthase A; PFAM: Malate synthase family protein; PRIAM: Malate synthase; SPTR: Malate synthase; TIGRFAM: malate synthase A; PFAM: Malate synthase; TIGRFAM: malate synthase A; Belongs to the malate synthase family.
   
    0.677
ADU47908.1
KEGG: tbi:Tbis_2132 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.648
ADU47907.1
Two component transcriptional regulator, LytTR family; COGs: COG3279 Response regulator of the LytR/AlgR family; InterPro IPR001789: IPR007492; KEGG: nca:Noca_0357 response regulator receiver; PFAM: response regulator receiver; LytTr DNA-binding region; SMART: response regulator receiver; SPTR: Response regulator receiver; PFAM: Response regulator receiver domain; LytTr DNA-binding domain.
       0.595
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
  
 0.594
ADU47906.1
Signal transduction histidine kinase, LytS; COGs: COG3275 Putative regulator of cell autolysis; InterPro IPR010559: IPR003594; KEGG: nca:Noca_0358 histidine kinase internal region; PFAM: histidine kinase internal region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Histidine kinase internal region; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
       0.538
ADU48771.1
COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR020845: IPR000873; KEGG: sro:Sros_1890 propionate--CoA ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: Acetyl-CoA synthetase; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme.
  
  
 0.535
ADU46915.1
COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: cai:Caci_4507 acetate/CoA ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: Acetate/CoA ligase; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme.
  
  
 0.520
ADU47794.1
Hypothetical protein; InterPro IPR017523; KEGG: kse:Ksed_08510 conserved hypothetical protein TIGR03089; SPTR: Putative uncharacterized protein; TIGRFAM: conserved hypothetical protein TIGR03089.
  
  
 0.520
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.