| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADU46627.1 | ADU47941.1 | Intca_0065 | Intca_1425 | Cell elongation-specific peptidoglycan biosynthesis regulator RodA; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182; KEGG: kra:Krad_0074 cell cycle protein; PFAM: cell cycle protein; SPTR: Putative FtsW/RodA/SpoVE family cell cycle protein; PFAM: Cell cycle protein; Belongs to the SEDS family. | Competence protein ComEA helix-hairpin-helix repeat protein; COGs: COG1555 DNA uptake protein and related DNA-binding protein; InterPro IPR004509: IPR019554; KEGG: kse:Ksed_17330 DNA uptake protein; PFAM: Soluble ligand binding domain; SPTR: Putative DNA-binding protein; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; PFAM: SLBB domain; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat region; comEA protein. | 0.494 |
| ADU46972.1 | ADU47941.1 | Intca_0424 | Intca_1425 | GCN5-related N-acetyltransferase; COGs: COG4552 acetyltransferase involved in intracellular survival and related acetyltransferase; InterPro IPR000182; KEGG: kfl:Kfla_4406 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase; PFAM: Acetyltransferase (GNAT) family. | Competence protein ComEA helix-hairpin-helix repeat protein; COGs: COG1555 DNA uptake protein and related DNA-binding protein; InterPro IPR004509: IPR019554; KEGG: kse:Ksed_17330 DNA uptake protein; PFAM: Soluble ligand binding domain; SPTR: Putative DNA-binding protein; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; PFAM: SLBB domain; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat region; comEA protein. | 0.634 |
| ADU47180.1 | ADU47941.1 | Intca_0635 | Intca_1425 | COGs: COG1316 Transcriptional regulator; InterPro IPR004474; KEGG: kra:Krad_3901 cell envelope-related transcriptional attenuator; PFAM: cell envelope-related transcriptional attenuator; SPTR: Cell envelope-related transcriptional attenuator; TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain. | Competence protein ComEA helix-hairpin-helix repeat protein; COGs: COG1555 DNA uptake protein and related DNA-binding protein; InterPro IPR004509: IPR019554; KEGG: kse:Ksed_17330 DNA uptake protein; PFAM: Soluble ligand binding domain; SPTR: Putative DNA-binding protein; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; PFAM: SLBB domain; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat region; comEA protein. | 0.517 |
| ADU47671.1 | ADU47941.1 | Intca_1152 | Intca_1425 | COGs: COG1316 Transcriptional regulator; InterPro IPR004474; KEGG: bfa:Bfae_09330 cell envelope-related function transcriptional attenuator common domain; PFAM: cell envelope-related transcriptional attenuator; SPTR: Putative transcriptional regulator; TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain. | Competence protein ComEA helix-hairpin-helix repeat protein; COGs: COG1555 DNA uptake protein and related DNA-binding protein; InterPro IPR004509: IPR019554; KEGG: kse:Ksed_17330 DNA uptake protein; PFAM: Soluble ligand binding domain; SPTR: Putative DNA-binding protein; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; PFAM: SLBB domain; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat region; comEA protein. | 0.597 |
| ADU47707.1 | ADU47941.1 | Intca_1189 | Intca_1425 | COGs: COG1316 Transcriptional regulator; InterPro IPR004474; KEGG: tcu:Tcur_4461 cell envelope-related transcriptional attenuator; PFAM: cell envelope-related transcriptional attenuator; SPTR: Putative transcriptional regulator; TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain. | Competence protein ComEA helix-hairpin-helix repeat protein; COGs: COG1555 DNA uptake protein and related DNA-binding protein; InterPro IPR004509: IPR019554; KEGG: kse:Ksed_17330 DNA uptake protein; PFAM: Soluble ligand binding domain; SPTR: Putative DNA-binding protein; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; PFAM: SLBB domain; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat region; comEA protein. | 0.576 |
| ADU47795.1 | ADU47941.1 | Intca_1277 | Intca_1425 | COGs: COG1316 Transcriptional regulator; InterPro IPR004474; KEGG: kse:Ksed_08470 cell envelope-related function transcriptional attenuator common domain protein; PFAM: cell envelope-related transcriptional attenuator; SPTR: Cell envelope-related transcriptional attenuator; TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain. | Competence protein ComEA helix-hairpin-helix repeat protein; COGs: COG1555 DNA uptake protein and related DNA-binding protein; InterPro IPR004509: IPR019554; KEGG: kse:Ksed_17330 DNA uptake protein; PFAM: Soluble ligand binding domain; SPTR: Putative DNA-binding protein; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; PFAM: SLBB domain; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat region; comEA protein. | 0.502 |
| ADU47941.1 | ADU46627.1 | Intca_1425 | Intca_0065 | Competence protein ComEA helix-hairpin-helix repeat protein; COGs: COG1555 DNA uptake protein and related DNA-binding protein; InterPro IPR004509: IPR019554; KEGG: kse:Ksed_17330 DNA uptake protein; PFAM: Soluble ligand binding domain; SPTR: Putative DNA-binding protein; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; PFAM: SLBB domain; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat region; comEA protein. | Cell elongation-specific peptidoglycan biosynthesis regulator RodA; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182; KEGG: kra:Krad_0074 cell cycle protein; PFAM: cell cycle protein; SPTR: Putative FtsW/RodA/SpoVE family cell cycle protein; PFAM: Cell cycle protein; Belongs to the SEDS family. | 0.494 |
| ADU47941.1 | ADU46972.1 | Intca_1425 | Intca_0424 | Competence protein ComEA helix-hairpin-helix repeat protein; COGs: COG1555 DNA uptake protein and related DNA-binding protein; InterPro IPR004509: IPR019554; KEGG: kse:Ksed_17330 DNA uptake protein; PFAM: Soluble ligand binding domain; SPTR: Putative DNA-binding protein; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; PFAM: SLBB domain; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat region; comEA protein. | GCN5-related N-acetyltransferase; COGs: COG4552 acetyltransferase involved in intracellular survival and related acetyltransferase; InterPro IPR000182; KEGG: kfl:Kfla_4406 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase; PFAM: Acetyltransferase (GNAT) family. | 0.634 |
| ADU47941.1 | ADU47180.1 | Intca_1425 | Intca_0635 | Competence protein ComEA helix-hairpin-helix repeat protein; COGs: COG1555 DNA uptake protein and related DNA-binding protein; InterPro IPR004509: IPR019554; KEGG: kse:Ksed_17330 DNA uptake protein; PFAM: Soluble ligand binding domain; SPTR: Putative DNA-binding protein; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; PFAM: SLBB domain; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat region; comEA protein. | COGs: COG1316 Transcriptional regulator; InterPro IPR004474; KEGG: kra:Krad_3901 cell envelope-related transcriptional attenuator; PFAM: cell envelope-related transcriptional attenuator; SPTR: Cell envelope-related transcriptional attenuator; TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain. | 0.517 |
| ADU47941.1 | ADU47671.1 | Intca_1425 | Intca_1152 | Competence protein ComEA helix-hairpin-helix repeat protein; COGs: COG1555 DNA uptake protein and related DNA-binding protein; InterPro IPR004509: IPR019554; KEGG: kse:Ksed_17330 DNA uptake protein; PFAM: Soluble ligand binding domain; SPTR: Putative DNA-binding protein; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; PFAM: SLBB domain; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat region; comEA protein. | COGs: COG1316 Transcriptional regulator; InterPro IPR004474; KEGG: bfa:Bfae_09330 cell envelope-related function transcriptional attenuator common domain; PFAM: cell envelope-related transcriptional attenuator; SPTR: Putative transcriptional regulator; TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain. | 0.597 |
| ADU47941.1 | ADU47707.1 | Intca_1425 | Intca_1189 | Competence protein ComEA helix-hairpin-helix repeat protein; COGs: COG1555 DNA uptake protein and related DNA-binding protein; InterPro IPR004509: IPR019554; KEGG: kse:Ksed_17330 DNA uptake protein; PFAM: Soluble ligand binding domain; SPTR: Putative DNA-binding protein; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; PFAM: SLBB domain; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat region; comEA protein. | COGs: COG1316 Transcriptional regulator; InterPro IPR004474; KEGG: tcu:Tcur_4461 cell envelope-related transcriptional attenuator; PFAM: cell envelope-related transcriptional attenuator; SPTR: Putative transcriptional regulator; TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain. | 0.576 |
| ADU47941.1 | ADU47795.1 | Intca_1425 | Intca_1277 | Competence protein ComEA helix-hairpin-helix repeat protein; COGs: COG1555 DNA uptake protein and related DNA-binding protein; InterPro IPR004509: IPR019554; KEGG: kse:Ksed_17330 DNA uptake protein; PFAM: Soluble ligand binding domain; SPTR: Putative DNA-binding protein; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; PFAM: SLBB domain; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat region; comEA protein. | COGs: COG1316 Transcriptional regulator; InterPro IPR004474; KEGG: kse:Ksed_08470 cell envelope-related function transcriptional attenuator common domain protein; PFAM: cell envelope-related transcriptional attenuator; SPTR: Cell envelope-related transcriptional attenuator; TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain. | 0.502 |
| ADU47941.1 | ADU47942.1 | Intca_1425 | Intca_1426 | Competence protein ComEA helix-hairpin-helix repeat protein; COGs: COG1555 DNA uptake protein and related DNA-binding protein; InterPro IPR004509: IPR019554; KEGG: kse:Ksed_17330 DNA uptake protein; PFAM: Soluble ligand binding domain; SPTR: Putative DNA-binding protein; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; PFAM: SLBB domain; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat region; comEA protein. | ComEC/Rec2-related protein; COGs: COG2333 hydrolase (metallo-beta-lactamase superfamily); InterPro IPR004477; KEGG: kra:Krad_3434 DNA internalization-related competence protein ComEC/Rec2; PFAM: ComEC/Rec2-related protein; SPTR: Putative integral membrane protein; TIGRFAM: ComEC/Rec2-related protein; PFAM: Competence protein; Metallo-beta-lactamase superfamily; TIGRFAM: ComEC/Rec2-related protein; DNA internalization-related competence protein ComEC/Rec2. | 0.942 |
| ADU47941.1 | ADU48104.1 | Intca_1425 | Intca_1591 | Competence protein ComEA helix-hairpin-helix repeat protein; COGs: COG1555 DNA uptake protein and related DNA-binding protein; InterPro IPR004509: IPR019554; KEGG: kse:Ksed_17330 DNA uptake protein; PFAM: Soluble ligand binding domain; SPTR: Putative DNA-binding protein; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; PFAM: SLBB domain; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat region; comEA protein. | Peptidase A24A prepilin type IV; InterPro IPR000045; KEGG: kra:Krad_3020 peptidase A24A domain protein; PFAM: peptidase A24A prepilin type IV; SPTR: Putative uncharacterized protein; PFAM: Type IV leader peptidase family. | 0.636 |
| ADU47941.1 | ADU48790.1 | Intca_1425 | Intca_2281 | Competence protein ComEA helix-hairpin-helix repeat protein; COGs: COG1555 DNA uptake protein and related DNA-binding protein; InterPro IPR004509: IPR019554; KEGG: kse:Ksed_17330 DNA uptake protein; PFAM: Soluble ligand binding domain; SPTR: Putative DNA-binding protein; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; PFAM: SLBB domain; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat region; comEA protein. | DNA protecting protein DprA; COGs: COG0758 Rossmann fold nucleotide-binding protein involved in DNA uptake; InterPro IPR003488; KEGG: kra:Krad_1409 DNA protecting protein DprA; PFAM: SMF family protein; SPTR: DNA protecting protein DprA; TIGRFAM: DNA protecting protein DprA; PFAM: DNA recombination-mediator protein A; TIGRFAM: DNA protecting protein DprA. | 0.425 |
| ADU47941.1 | purU | Intca_1425 | Intca_1424 | Competence protein ComEA helix-hairpin-helix repeat protein; COGs: COG1555 DNA uptake protein and related DNA-binding protein; InterPro IPR004509: IPR019554; KEGG: kse:Ksed_17330 DNA uptake protein; PFAM: Soluble ligand binding domain; SPTR: Putative DNA-binding protein; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; PFAM: SLBB domain; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat region; comEA protein. | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). | 0.495 |
| ADU47942.1 | ADU47941.1 | Intca_1426 | Intca_1425 | ComEC/Rec2-related protein; COGs: COG2333 hydrolase (metallo-beta-lactamase superfamily); InterPro IPR004477; KEGG: kra:Krad_3434 DNA internalization-related competence protein ComEC/Rec2; PFAM: ComEC/Rec2-related protein; SPTR: Putative integral membrane protein; TIGRFAM: ComEC/Rec2-related protein; PFAM: Competence protein; Metallo-beta-lactamase superfamily; TIGRFAM: ComEC/Rec2-related protein; DNA internalization-related competence protein ComEC/Rec2. | Competence protein ComEA helix-hairpin-helix repeat protein; COGs: COG1555 DNA uptake protein and related DNA-binding protein; InterPro IPR004509: IPR019554; KEGG: kse:Ksed_17330 DNA uptake protein; PFAM: Soluble ligand binding domain; SPTR: Putative DNA-binding protein; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; PFAM: SLBB domain; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat region; comEA protein. | 0.942 |
| ADU47942.1 | ADU48104.1 | Intca_1426 | Intca_1591 | ComEC/Rec2-related protein; COGs: COG2333 hydrolase (metallo-beta-lactamase superfamily); InterPro IPR004477; KEGG: kra:Krad_3434 DNA internalization-related competence protein ComEC/Rec2; PFAM: ComEC/Rec2-related protein; SPTR: Putative integral membrane protein; TIGRFAM: ComEC/Rec2-related protein; PFAM: Competence protein; Metallo-beta-lactamase superfamily; TIGRFAM: ComEC/Rec2-related protein; DNA internalization-related competence protein ComEC/Rec2. | Peptidase A24A prepilin type IV; InterPro IPR000045; KEGG: kra:Krad_3020 peptidase A24A domain protein; PFAM: peptidase A24A prepilin type IV; SPTR: Putative uncharacterized protein; PFAM: Type IV leader peptidase family. | 0.835 |
| ADU47942.1 | ADU48790.1 | Intca_1426 | Intca_2281 | ComEC/Rec2-related protein; COGs: COG2333 hydrolase (metallo-beta-lactamase superfamily); InterPro IPR004477; KEGG: kra:Krad_3434 DNA internalization-related competence protein ComEC/Rec2; PFAM: ComEC/Rec2-related protein; SPTR: Putative integral membrane protein; TIGRFAM: ComEC/Rec2-related protein; PFAM: Competence protein; Metallo-beta-lactamase superfamily; TIGRFAM: ComEC/Rec2-related protein; DNA internalization-related competence protein ComEC/Rec2. | DNA protecting protein DprA; COGs: COG0758 Rossmann fold nucleotide-binding protein involved in DNA uptake; InterPro IPR003488; KEGG: kra:Krad_1409 DNA protecting protein DprA; PFAM: SMF family protein; SPTR: DNA protecting protein DprA; TIGRFAM: DNA protecting protein DprA; PFAM: DNA recombination-mediator protein A; TIGRFAM: DNA protecting protein DprA. | 0.889 |
| ADU47942.1 | purU | Intca_1426 | Intca_1424 | ComEC/Rec2-related protein; COGs: COG2333 hydrolase (metallo-beta-lactamase superfamily); InterPro IPR004477; KEGG: kra:Krad_3434 DNA internalization-related competence protein ComEC/Rec2; PFAM: ComEC/Rec2-related protein; SPTR: Putative integral membrane protein; TIGRFAM: ComEC/Rec2-related protein; PFAM: Competence protein; Metallo-beta-lactamase superfamily; TIGRFAM: ComEC/Rec2-related protein; DNA internalization-related competence protein ComEC/Rec2. | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). | 0.492 |