STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
ADU47941.1Competence protein ComEA helix-hairpin-helix repeat protein; COGs: COG1555 DNA uptake protein and related DNA-binding protein; InterPro IPR004509: IPR019554; KEGG: kse:Ksed_17330 DNA uptake protein; PFAM: Soluble ligand binding domain; SPTR: Putative DNA-binding protein; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; PFAM: SLBB domain; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat region; comEA protein. (344 aa)    
Predicted Functional Partners:
ADU47942.1
ComEC/Rec2-related protein; COGs: COG2333 hydrolase (metallo-beta-lactamase superfamily); InterPro IPR004477; KEGG: kra:Krad_3434 DNA internalization-related competence protein ComEC/Rec2; PFAM: ComEC/Rec2-related protein; SPTR: Putative integral membrane protein; TIGRFAM: ComEC/Rec2-related protein; PFAM: Competence protein; Metallo-beta-lactamase superfamily; TIGRFAM: ComEC/Rec2-related protein; DNA internalization-related competence protein ComEC/Rec2.
 
  
 0.942
ADU48104.1
Peptidase A24A prepilin type IV; InterPro IPR000045; KEGG: kra:Krad_3020 peptidase A24A domain protein; PFAM: peptidase A24A prepilin type IV; SPTR: Putative uncharacterized protein; PFAM: Type IV leader peptidase family.
   
  
 0.636
ADU46972.1
GCN5-related N-acetyltransferase; COGs: COG4552 acetyltransferase involved in intracellular survival and related acetyltransferase; InterPro IPR000182; KEGG: kfl:Kfla_4406 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase; PFAM: Acetyltransferase (GNAT) family.
  
    0.634
ADU47671.1
COGs: COG1316 Transcriptional regulator; InterPro IPR004474; KEGG: bfa:Bfae_09330 cell envelope-related function transcriptional attenuator common domain; PFAM: cell envelope-related transcriptional attenuator; SPTR: Putative transcriptional regulator; TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain.
 
     0.597
ADU47707.1
COGs: COG1316 Transcriptional regulator; InterPro IPR004474; KEGG: tcu:Tcur_4461 cell envelope-related transcriptional attenuator; PFAM: cell envelope-related transcriptional attenuator; SPTR: Putative transcriptional regulator; TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain.
 
     0.576
ADU47180.1
COGs: COG1316 Transcriptional regulator; InterPro IPR004474; KEGG: kra:Krad_3901 cell envelope-related transcriptional attenuator; PFAM: cell envelope-related transcriptional attenuator; SPTR: Cell envelope-related transcriptional attenuator; TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain.
 
     0.517
ADU47795.1
COGs: COG1316 Transcriptional regulator; InterPro IPR004474; KEGG: kse:Ksed_08470 cell envelope-related function transcriptional attenuator common domain protein; PFAM: cell envelope-related transcriptional attenuator; SPTR: Cell envelope-related transcriptional attenuator; TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain.
 
     0.502
purU
Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).
       0.495
ADU46627.1
Cell elongation-specific peptidoglycan biosynthesis regulator RodA; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182; KEGG: kra:Krad_0074 cell cycle protein; PFAM: cell cycle protein; SPTR: Putative FtsW/RodA/SpoVE family cell cycle protein; PFAM: Cell cycle protein; Belongs to the SEDS family.
 
    0.494
ADU48790.1
DNA protecting protein DprA; COGs: COG0758 Rossmann fold nucleotide-binding protein involved in DNA uptake; InterPro IPR003488; KEGG: kra:Krad_1409 DNA protecting protein DprA; PFAM: SMF family protein; SPTR: DNA protecting protein DprA; TIGRFAM: DNA protecting protein DprA; PFAM: DNA recombination-mediator protein A; TIGRFAM: DNA protecting protein DprA.
 
  
 0.425
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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