STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
ADU47976.1Transcriptional regulator, LuxR family; COGs: COG3899 ATPase; InterPro IPR000792: IPR019734; KEGG: sti:Sthe_2247 transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; Tetratricopeptide repeat; SPTR: Transcriptional regulator, LuxR family; PFAM: Bacterial regulatory proteins, luxR family. (871 aa)    
Predicted Functional Partners:
ADU49815.1
COGs: COG4585 Signal transduction histidine kinase; InterPro IPR003018: IPR011712: IPR003594; KEGG: saq:Sare_1529 GAF sensor signal transduction histidine kinase; PFAM: GAF domain protein; histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: GAF domain protein; SPTR: GAF sensor signal transduction histidine kinase; PFAM: Histidine kinase; GAF domain.
 
 
 0.767
ADU47498.1
COGs: COG4585 Signal transduction histidine kinase; InterPro IPR007168: IPR003594; KEGG: art:Arth_2999 putative signal transduction histidine kinase; PFAM: PspC domain protein; ATP-binding region ATPase domain protein; SPTR: Putative signal transduction histidine kinase; PFAM: PspC domain.
 
 
 0.689
ADU47975.1
KEGG: nca:Noca_4891 putative gualylate cyclase protein; SPTR: Putative gualylate cyclase protein.
 
 
 0.680
ADU46986.1
PAS/PAC sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR001789: IPR000014: IPR000700: IPR 005561: IPR013656: IPR003661: IPR003594: IPR013767: IPR004358; KEGG: ami:Amir_3954 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; response regulator receiver; PAS fold domain protein; ANTAR domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Multi [...]
  
 
 0.647
ADU49308.1
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR000595: IPR003594: IPR005467: IPR004358; KEGG: rha:RHA1_ro04003 sensor kinase, two-component system; PFAM: ATP-binding region ATPase domain protein; cyclic nucleotide-binding; SMART: ATP-binding region ATPase domain protein; cyclic nucleotide-binding; SPTR: Histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
  
 
 0.546
ADU47059.1
Protein of unknown function DUF306 Meta and HslJ; COGs: COG3187 Heat shock protein; InterPro IPR005184; KEGG: rer:RER_23460 hypothetical protein; PFAM: protein of unknown function DUF306 Meta and HslJ; SPTR: Putative uncharacterized protein; PFAM: META domain.
  
    0.538
ADU47974.1
KEGG: sus:Acid_3612 hypothetical protein; SPTR: Putative uncharacterized protein.
     
 0.487
ADU47978.1
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG2072 flavoprotein involved in K+ transport; InterPro IPR013027: IPR001327; KEGG: rha:RHA1_ro04494 potassium uptake protein; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Possible potassium uptake protein; PFAM: Pyridine nucleotide-disulphide oxidoreductase.
       0.484
ADU47977.1
KEGG: bcv:Bcav_0070 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.482
ADU49393.1
ATP-binding region ATPase domain protein; InterPro IPR003018: IPR003594: IPR018247; KEGG: cai:Caci_4163 putative PAS/PAC sensor protein; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; SPTR: PAS/PAC sensor hybrid histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
  
 0.479
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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