STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU47984.1NERD domain protein; InterPro IPR011528; KEGG: mgi:Mflv_5176 hypothetical protein; PFAM: NERD domain protein; SPTR: Putative uncharacterized protein; PFAM: Nuclease-related domain; Uncharacterized conserved protein (DUF2075). (560 aa)    
Predicted Functional Partners:
ADU48489.1
DNA polymerase III, epsilon subunit; COGs: COG0322 Nuclease subunit of the excinuclease complex; InterPro IPR013520: IPR000305: IPR006055: IPR006054; KEGG: kra:Krad_3247 hypothetical protein; PFAM: Exonuclease RNase T and DNA polymerase III; Excinuclease ABC C subunit domain protein; PRIAM: DNA-directed DNA polymerase; SMART: Exonuclease; Excinuclease ABC C subunit domain protein; SPTR: Putative uncharacterized protein; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease; GIY-YIG catalytic domain; TIGRFAM: exonuclease, DNA polymerase III, epsilon subunit family.
  
  
 0.597
ADU47983.1
UspA domain-containing protein; InterPro IPR006015: IPR006016; KEGG: sna:Snas_3659 UspA domain-containing protein; PFAM: UspA domain-containing protein; SPTR: UspA domain protein; PFAM: Universal stress protein family.
       0.596
ADU47985.1
COGs: COG0589 Universal stress protein UspA and related nucleotide-binding protein; InterPro IPR006015: IPR006016; KEGG: saq:Sare_1891 UspA domain-containing protein; PFAM: UspA domain-containing protein; SPTR: Putative Usp family protein; PFAM: Universal stress protein family.
       0.547
ligA
DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
  
  
 0.536
ADU49059.1
ATP-dependent DNA helicase, Rep family; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR002121: IPR014016: IPR014017: IPR000212; KEGG: kra:Krad_1179 UvrD/REP helicase; PFAM: UvrD/REP helicase; HRDC domain protein; SMART: HRDC domain protein; SPTR: Putative ATP-dependent DNA helicase; manually curated; PFAM: HRDC domain; UvrD/REP helicase.
 
 
 0.531
ADU49559.1
Peptidase M12A astacin; InterPro IPR006026: IPR001506: IPR007280; KEGG: lch:Lcho_4313 peptidase domain-containing protein; PFAM: peptidase M12A astacin; peptidase domain protein; SMART: peptidase metallopeptidase; SPTR: Peptidase domain protein; PFAM: Astacin (Peptidase family M12A).
 
    0.522
recA
recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.517
ADU47066.1
Type II secretion system F domain; InterPro IPR018076; KEGG: kse:Ksed_25280 Flp pilus assembly protein TadC; PFAM: Type II secretion system F domain; SPTR: Putative uncharacterized protein; PFAM: Bacterial type II secretion system protein F domain.
  
     0.516
ADU49832.1
Metallophosphoesterase; InterPro IPR004843; KEGG: bfa:Bfae_11330 predicted phosphohydrolase; PFAM: metallophosphoesterase; SPTR: Putative integral membrane protein; PFAM: Calcineurin-like phosphoesterase.
 
 
   0.514
ADU46758.1
Amidohydrolase; COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680; KEGG: bja:blr0249 hypothetical protein; PFAM: amidohydrolase; SPTR: Amidohydrolase; PFAM: Amidohydrolase family.
 
 
   0.500
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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