Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADU47987.1Tex-like protein; COGs: COG2183 Transcriptional accessory protein; InterPro IPR018974: IPR003029: IPR006641; KEGG: amd:AMED_1551 transcriptional accessory protein; PFAM: Tex-like protein-like; RNA binding S1 domain protein; SMART: Resolvase RNase H domain protein fold; SPTR: RNA binding S1 domain protein; PFAM: Tex-like protein N-terminal domain; S1 RNA binding domain; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat region. (804 aa)    
Predicted Functional Partners:
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.857
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.852
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
  0.818
ADU46835.1
KEGG: ecx:EcHS_A2423 hypothetical protein; SPTR: Putative uncharacterized protein.
    
 0.521
ADU48076.1
KEGG: sen:SACE_5253 hypothetical protein; SPTR: Putative uncharacterized protein; manually curated.
    
 0.521
ADU48391.1
InterPro IPR001440: IPR019734: IPR013026; KEGG: cyp:PCC8801_1300 TPR repeat-containing protein; PFAM: Tetratricopeptide TPR_1 repeat-containing protein; SMART: Tetratricopeptide repeat; SPTR: TPR repeat-containing protein; PFAM: Tetratricopeptide repeat.
    
 0.521
ADU49390.1
KEGG: pjd:Pjdr2_2870 hypothetical protein; SPTR: Putative uncharacterized protein.
    
 0.521
ADU47986.1
KEGG: pfr:PFREUD_17160 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Activator of Hsp90 ATPase homolog 1-like protein.
       0.476
nnrE
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
   
   0.467
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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