STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU47999.1COGs: COG4630 Xanthine dehydrogenase iron-sulfur cluster and FAD-binding subunit A; InterProIPR006058: IPR001041: IPR002888: IPR002346: IPR 005107: IPR016166; KEGG: nca:Noca_1636 molybdopterin dehydrogenase, FAD-binding; PFAM: molybdopterin dehydrogenase FAD-binding; [2Fe-2S]-binding domain-containing protein; ferredoxin; CO dehydrogenase flavoprotein domain protein; SPTR: Dehydrogenase; PFAM: 2Fe-2S iron-sulfur cluster binding domain; FAD binding domain in molybdopterin dehydrogenase; [2Fe-2S] binding domain; CO dehydrogenase flavoprotein C-terminal domain; TIGRFAM: xanthine dehydroge [...] (559 aa)    
Predicted Functional Partners:
ADU47998.1
COGs: COG4631 Xanthine dehydrogenase molybdopterin-binding subunit B; InterPro IPR014309: IPR000674: IPR008274; KEGG: nca:Noca_1637 xanthine oxidase; PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; PRIAM: Xanthine oxidase; SPTR: Xanthine oxidase; TIGRFAM: xanthine dehydrogenase, molybdopterin binding subunit; PFAM: Molybdopterin-binding domain of aldehyde dehydrogenase; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; TIGRFAM: xanthine dehydrogenase, molybdopterin binding subunit.
 0.999
ADU47996.1
COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680; KEGG: msv:Mesil_1795 guanine deaminase; PFAM: amidohydrolase; SPTR: Amidohydrolase; PFAM: Amidohydrolase family; TIGRFAM: guanine deaminase.
 
  
  0.994
ADU47997.1
Molybdenum cofactor sulfurylase; COGs: COG1975 Xanthine and CO dehydrogenase maturation factor XdhC/CoxF family; InterPro IPR014308: IPR003777; KEGG: sco:SCO4973 hypothetical protein; PFAM: protein of unknown function DUF182; SPTR: Putative uncharacterized protein; TIGRFAM: xanthine dehydrogenase accessory protein XdhC; PFAM: XdhC and CoxI family; TIGRFAM: xanthine dehydrogenase accessory protein XdhC.
 
  
 0.966
ADU49326.1
COGs: COG1957 Inosine-uridine nucleoside N-ribohydrolase; InterPro IPR001910; KEGG: nca:Noca_0542 inosine/uridine-preferring nucleoside hydrolase; PFAM: Inosine/uridine-preferring nucleoside hydrolase; SPTR: Inosine/uridine-preferring nucleoside hydrolase; PFAM: Inosine-uridine preferring nucleoside hydrolase.
 
  
  0.915
ADU47143.1
COGs: COG0634 Hypoxanthine-guanine phosphoribosyltransferase; InterPro IPR000836: IPR005904; KEGG: kse:Ksed_24790 hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; PRIAM: Hypoxanthine phosphoribosyltransferase; SPTR: Putative hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; manually curated; PFAM: Phosphoribosyl transferase domain; TIGRFAM: hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
     
  0.900
ADU47743.1
Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
     
  0.900
ADU47604.1
Xanthine dehydrogenase, molybdenum binding subunit apoprotein; COGs: COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL/CutL homologs; InterPro IPR000674: IPR008274; KEGG: svi:Svir_20920 xanthine dehydrogenase, molybdenum binding subunit apoprotein; PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; SPTR: Probable dehydrogenase/oxidase; PFAM: Molybdopterin-binding domain of aldehyde dehydrogenase; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain.
     0.723
ADU46673.1
Xanthine dehydrogenase, molybdenum binding subunit apoprotein; COGs: COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL/CutL homologs; InterPro IPR000674: IPR008274; KEGG: nca:Noca_3969 xanthine dehydrogenase, molybdenum binding subunit apoprotein; PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; SPTR: Nicotine dehydrogenase chain C; PFAM: Molybdopterin-binding domain of aldehyde dehydrogenase; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; TIGRFAM: carbon-monoxid [...]
     0.709
ADU46666.1
Protein of unknown function DUF182; COGs: COG1975 Xanthine and CO dehydrogenase maturation factor XdhC/CoxF family; InterPro IPR003777; KEGG: nca:Noca_3973 hypothetical protein; PFAM: protein of unknown function DUF182; SPTR: Putative uncharacterized protein; PFAM: XdhC and CoxI family.
 
  
 0.541
ADU48000.1
KEGG: kfl:Kfla_4292 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.458
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
Server load: low (26%) [HD]