Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADU48021.1Protein-tyrosine phosphatase, low molecular weight; COGs: COG0394 Protein-tyrosine-phosphatase; InterPro IPR017867; KEGG: nca:Noca_4205 adenylylsulfate kinase; PFAM: Protein-tyrosine phosphatase, low molecular weight; SMART: Protein-tyrosine phosphatase, low molecular weight; SPTR: Ptp; PFAM: Low molecular weight phosphotyrosine protein phosphatase. (184 aa)    
Predicted Functional Partners:
ADU47694.1
COGs: COG0394 Protein-tyrosine-phosphatase; InterPro IPR017867: IPR000106; KEGG: aau:AAur_3227 low molecular weight phosphotyrosine protein phosphatase; PFAM: Protein-tyrosine phosphatase, low molecular weight; SMART: Protein-tyrosine phosphatase, low molecular weight; SPTR: Low molecular weight phosphotyrosine protein phosphatase; PFAM: Low molecular weight phosphotyrosine protein phosphatase.
  
     0.762
ADU47697.1
KEGG: aau:AAur_4128 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.627
ADU49127.1
2-nitropropane dioxygenase-like protein; KEGG: rmu:RMDY18_15750 dioxygenase related to 2-nitropropane dioxygenase; SPTR: Putative uncharacterized protein.
 
     0.613
sigA
RNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
     
 0.594
ADU47700.1
Capsular exopolysaccharide family; COGs: COG0489 ATPase involved in chromosome partitioning; InterPro IPR003856: IPR005702; KEGG: cmi:CMM_0908 putative tyrosine-protein kinase; PFAM: lipopolysaccharide biosynthesis protein; PRIAM: Non-specific protein-tyrosine kinase; SPTR: Putative tyrosine-protein kinase; TIGRFAM: capsular exopolysaccharide family; PFAM: Chain length determinant protein; CobQ/CobB/MinD/ParA nucleotide binding domain; TIGRFAM: capsular exopolysaccharide family.
 
 
 0.577
ADU49134.1
Lipopolysaccharide biosynthesis protein; COGs: COG0489 ATPase involved in chromosome partitioning; InterPro IPR003856; KEGG: cfl:Cfla_0897 capsular exopolysaccharide family; PFAM: lipopolysaccharide biosynthesis protein; SPTR: Putative uncharacterized protein; PFAM: Chain length determinant protein; CobQ/CobB/MinD/ParA nucleotide binding domain; TIGRFAM: capsular exopolysaccharide family.
 
 
 0.574
ADU47699.1
2-nitropropane dioxygenase-like protein; KEGG: rmu:RMDY18_15750 dioxygenase related to 2-nitropropane dioxygenase; SPTR: Putative uncharacterized protein.
 
     0.534
ADU48591.1
Arsenical-resistance protein; COGs: COG0798 Arsenite efflux pump ACR3 and related permease; InterPro IPR002657: IPR004706; KEGG: nfa:pnf2250 putative arsenic resistance transporter; PFAM: Bile acid:sodium symporter; SPTR: Putative arsenic resistance transporter; TIGRFAM: arsenical-resistance protein; PFAM: Sodium Bile acid symporter family; TIGRFAM: arsenical-resistance protein.
  
  
 0.467
ADU47494.1
Glycosyl hydrolase family 32 domain protein; COGs: COG1621 Beta-fructosidase (levanase/invertase); InterPro IPR013148; KEGG: fre:Franean1_7054 glycosyl hydrolase family 32 protein; PFAM: Glycosyl hydrolase family 32 domain protein; SPTR: Putative uncharacterized protein; PFAM: Glycosyl hydrolases family 32 N-terminal domain.
  
 
 0.462
ADU47601.1
Rhodanese domain protein; COGs: COG0491 Zn-dependent hydrolase including glyoxylase; InterPro IPR001763; KEGG: tfu:Tfu_3085 rhodanese-like protein; PFAM: Rhodanese domain protein; SPTR: Rhodanese-like protein; PFAM: Metallo-beta-lactamase superfamily; Rhodanese-like domain.
  
   0.444
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
Server load: low (14%) [HD]