STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU48049.1Gluconate kinase, SKI family; COGs: COG3265 Gluconate kinase; InterPro IPR006001: IPR000623; KEGG: art:Arth_0505 gluconate kinase; PFAM: shikimate kinase; PRIAM: Gluconokinase; SPTR: Gluconate kinase; TIGRFAM: carbohydrate kinase, thermoresistant glucokinase family; PFAM: Shikimate kinase; TIGRFAM: carbohydrate kinase, thermoresistant glucokinase family. (172 aa)    
Predicted Functional Partners:
ADU48976.1
6-phosphogluconate dehydrogenase (decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
  
 0.994
ADU46565.1
COGs: COG1023 6-phosphogluconate dehydrogenase; InterPro IPR006115: IPR006114: IPR004849: IPR006183; KEGG: kse:Ksed_00030 6-phosphogluconate dehydrogenase (decarboxylating); PFAM: 6-phosphogluconate dehydrogenase NAD-binding; 6-phosphogluconate dehydrogenase domain-containing protein; SPTR: 6-phosphogluconate dehydrogenase, decarboxylating; TIGRFAM: 6-phosphogluconate dehydrogenase, decarboxylating; manually curated; PFAM: 6-phosphogluconate dehydrogenase, C-terminal domain; NAD binding domain of 6-phosphogluconate dehydrogenase; TIGRFAM: 6-phosphogluconate dehydrogenase (decarboxylating).
  
 0.981
ADU48969.1
Carbohydrate kinase, FGGY; COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018484: IPR018485: IPR018483; KEGG: kse:Ksed_11390 pentulose/hexulose kinase; PFAM: Carbohydrate kinase, FGGY-like; SPTR: Pentulose/hexulose kinase; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; TIGRFAM: gluconate kinase, FGGY type; Belongs to the FGGY kinase family.
     
 0.944
pgl
6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
   
 0.929
ADU47645.1
COGs: COG2610 H+/gluconate symporter and related permease; InterPro IPR003474; KEGG: spe:Spro_1488 inner membrane permease YgbN; PFAM: Gluconate transporter; SPTR: Gluconate transporter; TIGRFAM: gluconate transporter; PFAM: GntP family permease; TIGRFAM: gluconate transporter.
 
  
 0.694
zwf-2
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
 
 
 
 0.490
zwf
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
 
 
 
 0.476
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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