STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
nadKATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (332 aa)    
Predicted Functional Partners:
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
    
 0.962
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
 
 
 0.956
ADU48079.1
COGs: COG1189 rRNA methylase; InterPro IPR002942: IPR002877: IPR004538; KEGG: mlu:Mlut_14230 hemolysin A; PFAM: RNA-binding S4 domain protein; ribosomal RNA methyltransferase RrmJ/FtsJ; SMART: RNA-binding S4 domain protein; SPTR: Hemolysin A; TIGRFAM: hemolysin A; PFAM: S4 domain; FtsJ-like methyltransferase; TIGRFAM: hemolysin TlyA family protein.
  
  
 0.944
ADU46940.1
COGs: COG3288 NAD/NADP transhydrogenase alpha subunit; InterPro IPR007886: IPR007698: IPR008143: IPR004571; KEGG: mva:Mvan_0120 NAD(P) transhydrogenase subunit alpha; PFAM: alanine dehydrogenase/PNT domain protein; SPTR: NAD(P) transhydrogenase, alpha subunit; TIGRFAM: NAD(P) transhydrogenase, alpha subunit; PFAM: Alanine dehydrogenase/PNT, C-terminal domain; Alanine dehydrogenase/PNT, N-terminal domain; TIGRFAM: NAD(P) transhydrogenase, alpha subunit.
     
 0.918
ADU46941.1
NAD(P)(+) transhydrogenase (AB-specific); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
     
 0.909
ADU49061.1
NAD(+) diphosphatase; COGs: COG2816 NTP pyrophosphohydrolase containing a Zn-finger probably nucleic-acid-binding; InterPro IPR015375: IPR015376: IPR000086: IPR020084; KEGG: tbi:Tbis_2968 NAD(+) diphosphatase; PFAM: NUDIX hydrolase; Zinc ribbon NADH pyrophosphatase; NADH pyrophosphatase-like; PRIAM: NAD(+) diphosphatase; SPTR: NADH pyrophosphatase; PFAM: NADH pyrophosphatase zinc ribbon domain; NUDIX domain; NADH pyrophosphatase-like rudimentary NUDIX domain.
     
 0.902
ADU48081.1
DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA.
 
   
 0.901
ADU48076.1
KEGG: sen:SACE_5253 hypothetical protein; SPTR: Putative uncharacterized protein; manually curated.
 
   
 0.794
ADU48077.1
HAD-superfamily hydrolase, subfamily IIA; COGs: COG0647 sugar phosphatase of the HAD superfamily; InterPro IPR005834: IPR006357; KEGG: sro:Sros_6062 sugar phosphatase of the HAD superfamily-like protein; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: Sugar phosphatase of the HAD superfamily-like protein; TIGRFAM: HAD-superfamily hydrolase, subfamily IIA; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Haloacid Dehalogenase Superfamily Class (subfamily) IIA.
     
 0.783
ADU48078.1
KEGG: mgi:Mflv_0916 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.773
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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