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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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alaSalanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (890 aa)    
Predicted Functional Partners:
glyQ
COGs: COG0751 Glycyl-tRNA synthetase beta subunit; InterPro IPR006194: IPR002310: IPR002311: IPR015944; KEGG: kfl:Kfla_5824 glycyl-tRNA synthetase, beta subunit; PFAM: glycyl-tRNA synthetase alpha subunit; glycyl-tRNA synthetase beta subunit; PRIAM: Glycine--tRNA ligase; SPTR: Glycyl-tRNA synthetase, beta subunit; TIGRFAM: glycyl-tRNA synthetase, beta subunit; glycyl-tRNA synthetase, alpha subunit; PFAM: Glycyl-tRNA synthetase beta subunit; Glycyl-tRNA synthetase alpha subunit; TIGRFAM: glycyl-tRNA synthetase, tetrameric type, beta subunit; glycyl-tRNA synthetase, tetrameric type, alph [...]
  
  
 0.979
ADU48101.1
Holliday junction resolvase YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.
 
  
 0.966
pheT
COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; InterProIPR002547: IPR005121: IPR004532: IPR005146: IPR 005147; KEGG: kra:Krad_3163 phenylalanyl-tRNA synthetase, beta subunit; PFAM: B3/4 domain protein; t-RNA-binding domain-containing protein; tRNA synthetase B5; ferredoxin-fold anticodon-binding; SPTR: Phenylalanyl-tRNA synthetase beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; PFAM: tRNA synthetase B5 domain; Ferredoxin-fold anticodon binding domain; B3/4 domain; Putative tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit, non-spiroch [...]
 
 
 0.940
mltG
Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.
  
    0.871
valS
valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner.
 
  
 0.865
ADU49764.1
COGs: COG3629 DNA-binding transcriptional activator of the SARP family; InterProIPR019775: IPR019782: IPR017986: IPR001680: IPR 001867: IPR005158; KEGG: nml:Namu_2911 transcriptional regulator, SARP family; PFAM: transcriptional activator domain; transcriptional regulator domain-containing protein; SPTR: Transcriptional regulator, SARP family; PFAM: Bacterial transcriptional activator domain; Transcriptional regulatory protein, C terminal.
  
 0.835
ADU46844.1
Hypothetical protein; KEGG: rrs:RoseRS_4025 NB-ARC domain-containing protein; SPTR: Putative WD-40 repeat protein.
   
 0.829
ADU46845.1
WD40 repeat, subgroup; InterPro IPR019781: IPR001680: IPR019782; KEGG: gob:Gobs_1160 WD40 repeat, subgroup; PFAM: WD40 repeat, subgroup; SPTR: WD40 repeat, subgroup; PFAM: WD domain, G-beta repeat.
   
 0.829
leuS
COGs: COG0495 Leucyl-tRNA synthetase; InterProIPR002302: IPR001412: IPR015413: IPR002300: IPR 013155; KEGG: bcv:Bcav_1730 leucyl-tRNA synthetase; PFAM: tRNA synthetase valyl/leucyl anticodon-binding; tRNA synthetase class I (M); aminoacyl-tRNA synthetase class Ia; SPTR: Leucyl-tRNA synthetase; TIGRFAM: leucyl-tRNA synthetase; PFAM: tRNA synthetases class I (I, L, M and V); tRNA synthetases class I (M); Anticodon-binding domain; TIGRFAM: leucyl-tRNA synthetase, eubacterial and mitochondrial family.
  
 
 0.809
thrS
Ser-tRNA(Thr) hydrolase; COGs: COG0441 Threonyl-tRNA synthetase; InterProIPR018158: IPR012947: IPR002314: IPR004154: IPR 002320: IPR006195; KEGG: kse:Ksed_15440 threonyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Threonyl/alanyl tRNA synthetase SAD; Anticodon-binding domain protein; SPTR: Threonyl-tRNA synthetase; TIGRFAM: threonyl-tRNA synthetase; PFAM: Anticodon binding domain; Threonyl and Alanyl tRNA synthetase second additional domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: threonyl-tRNA synthetase; Belongs to the class-II aminoacyl-t [...]
  
 
 0.796
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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