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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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aroQ3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (145 aa)    
Predicted Functional Partners:
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
 
 0.979
ADU48103.1
Shikimate dehydrogenase substrate binding domain protein; COGs: COG0169 Shikimate 5-dehydrogenase; InterPro IPR013708; KEGG: gob:Gobs_3155 shikimate-5-dehydrogenase; PFAM: Shikimate dehydrogenase substrate binding domain protein; SPTR: Shikimate-5-dehydrogenase; PFAM: Shikimate dehydrogenase substrate binding domain; TIGRFAM: shikimate-5-dehydrogenase, fungal AROM-type; shikimate 5-dehydrogenase; Belongs to the shikimate dehydrogenase family.
 
 
 0.897
aroK
Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
 
   
 0.810
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
  
 0.800
tig
Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.
  
  
 0.631
ADU48200.1
Protein translocase subunit secG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
  
    0.604
ADU49750.1
Peptidase M24; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR017871: IPR001131: IPR000994; KEGG: amd:AMED_4873 X-Pro dipeptidase; PFAM: peptidase M24; SPTR: Peptidase M24; PFAM: Metallopeptidase family M24; Creatinase/Prolidase N-terminal domain; Belongs to the peptidase M24B family.
 
  
 0.583
rplM
LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
    0.553
trpE
Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...]
     
 0.516
ADU48104.1
Peptidase A24A prepilin type IV; InterPro IPR000045; KEGG: kra:Krad_3020 peptidase A24A domain protein; PFAM: peptidase A24A prepilin type IV; SPTR: Putative uncharacterized protein; PFAM: Type IV leader peptidase family.
     
 0.508
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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