| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADU47314.1 | ADU48109.1 | Intca_0773 | Intca_1596 | COGs: COG1010 Precorrin-3B methylase; InterPro IPR000878: IPR006364: IPR006363; KEGG: nda:Ndas_1624 precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; SPTR: Precorrin-3B C17-methyltransferase; TIGRFAM: precorrin-3B C17-methyltransferase; precorrin-2 C20-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-3B C17-methyltransferase; precorrin-2 C20-methyltransferase. | COGs: COG3973 Superfamily I DNA and RNA helicase; InterPro IPR000408; KEGG: kra:Krad_0164 ATP-dependent DNA helicase; SPTR: Putative ATP-dependent DNA helicase. | 0.498 |
| ADU47314.1 | cobS | Intca_0773 | Intca_2012 | COGs: COG1010 Precorrin-3B methylase; InterPro IPR000878: IPR006364: IPR006363; KEGG: nda:Ndas_1624 precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; SPTR: Precorrin-3B C17-methyltransferase; TIGRFAM: precorrin-3B C17-methyltransferase; precorrin-2 C20-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-3B C17-methyltransferase; precorrin-2 C20-methyltransferase. | Cobalamin-5-phosphate synthase CobS; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.991 |
| ADU48109.1 | ADU47314.1 | Intca_1596 | Intca_0773 | COGs: COG3973 Superfamily I DNA and RNA helicase; InterPro IPR000408; KEGG: kra:Krad_0164 ATP-dependent DNA helicase; SPTR: Putative ATP-dependent DNA helicase. | COGs: COG1010 Precorrin-3B methylase; InterPro IPR000878: IPR006364: IPR006363; KEGG: nda:Ndas_1624 precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; SPTR: Precorrin-3B C17-methyltransferase; TIGRFAM: precorrin-3B C17-methyltransferase; precorrin-2 C20-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-3B C17-methyltransferase; precorrin-2 C20-methyltransferase. | 0.498 |
| ADU48109.1 | cobS | Intca_1596 | Intca_2012 | COGs: COG3973 Superfamily I DNA and RNA helicase; InterPro IPR000408; KEGG: kra:Krad_0164 ATP-dependent DNA helicase; SPTR: Putative ATP-dependent DNA helicase. | Cobalamin-5-phosphate synthase CobS; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.490 |
| ADU48109.1 | efp | Intca_1596 | Intca_1597 | COGs: COG3973 Superfamily I DNA and RNA helicase; InterPro IPR000408; KEGG: kra:Krad_0164 ATP-dependent DNA helicase; SPTR: Putative ATP-dependent DNA helicase. | Translation elongation factor P (EF-P); Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | 0.490 |
| ADU48109.1 | nusB | Intca_1596 | Intca_1598 | COGs: COG3973 Superfamily I DNA and RNA helicase; InterPro IPR000408; KEGG: kra:Krad_0164 ATP-dependent DNA helicase; SPTR: Putative ATP-dependent DNA helicase. | NusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.490 |
| ADU48109.1 | rbpA-2 | Intca_1596 | Intca_1797 | COGs: COG3973 Superfamily I DNA and RNA helicase; InterPro IPR000408; KEGG: kra:Krad_0164 ATP-dependent DNA helicase; SPTR: Putative ATP-dependent DNA helicase. | Hypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. | 0.746 |
| ADU48109.1 | rpoA | Intca_1596 | Intca_2724 | COGs: COG3973 Superfamily I DNA and RNA helicase; InterPro IPR000408; KEGG: kra:Krad_0164 ATP-dependent DNA helicase; SPTR: Putative ATP-dependent DNA helicase. | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.769 |
| ADU48109.1 | rpoB | Intca_1596 | Intca_2766 | COGs: COG3973 Superfamily I DNA and RNA helicase; InterPro IPR000408; KEGG: kra:Krad_0164 ATP-dependent DNA helicase; SPTR: Putative ATP-dependent DNA helicase. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.819 |
| ADU48109.1 | rpoC | Intca_1596 | Intca_2764 | COGs: COG3973 Superfamily I DNA and RNA helicase; InterPro IPR000408; KEGG: kra:Krad_0164 ATP-dependent DNA helicase; SPTR: Putative ATP-dependent DNA helicase. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.814 |
| ADU48109.1 | rpoZ | Intca_1596 | Intca_1610 | COGs: COG3973 Superfamily I DNA and RNA helicase; InterPro IPR000408; KEGG: kra:Krad_0164 ATP-dependent DNA helicase; SPTR: Putative ATP-dependent DNA helicase. | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.798 |
| ADU48109.1 | sigA | Intca_1596 | Intca_1505 | COGs: COG3973 Superfamily I DNA and RNA helicase; InterPro IPR000408; KEGG: kra:Krad_0164 ATP-dependent DNA helicase; SPTR: Putative ATP-dependent DNA helicase. | RNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.790 |
| cobS | ADU47314.1 | Intca_2012 | Intca_0773 | Cobalamin-5-phosphate synthase CobS; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | COGs: COG1010 Precorrin-3B methylase; InterPro IPR000878: IPR006364: IPR006363; KEGG: nda:Ndas_1624 precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; SPTR: Precorrin-3B C17-methyltransferase; TIGRFAM: precorrin-3B C17-methyltransferase; precorrin-2 C20-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-3B C17-methyltransferase; precorrin-2 C20-methyltransferase. | 0.991 |
| cobS | ADU48109.1 | Intca_2012 | Intca_1596 | Cobalamin-5-phosphate synthase CobS; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | COGs: COG3973 Superfamily I DNA and RNA helicase; InterPro IPR000408; KEGG: kra:Krad_0164 ATP-dependent DNA helicase; SPTR: Putative ATP-dependent DNA helicase. | 0.490 |
| efp | ADU48109.1 | Intca_1597 | Intca_1596 | Translation elongation factor P (EF-P); Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | COGs: COG3973 Superfamily I DNA and RNA helicase; InterPro IPR000408; KEGG: kra:Krad_0164 ATP-dependent DNA helicase; SPTR: Putative ATP-dependent DNA helicase. | 0.490 |
| efp | nusB | Intca_1597 | Intca_1598 | Translation elongation factor P (EF-P); Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | NusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.886 |
| efp | rpoA | Intca_1597 | Intca_2724 | Translation elongation factor P (EF-P); Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.706 |
| efp | rpoB | Intca_1597 | Intca_2766 | Translation elongation factor P (EF-P); Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.521 |
| efp | rpoZ | Intca_1597 | Intca_1610 | Translation elongation factor P (EF-P); Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.689 |
| efp | sigA | Intca_1597 | Intca_1505 | Translation elongation factor P (EF-P); Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | RNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.563 |