| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADU48121.1 | ADU48140.1 | Intca_1608 | Intca_1627 | KEGG: sro:Sros_2812 hypothetical protein; SPTR: Putative uncharacterized protein. | KEGG: cfl:Cfla_1864 protein of unknown function DUF2581; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2581). | 0.715 |
| ADU48121.1 | ribH | Intca_1608 | Intca_1624 | KEGG: sro:Sros_2812 hypothetical protein; SPTR: Putative uncharacterized protein. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.406 |
| ADU48121.1 | rpsC | Intca_1608 | Intca_2750 | KEGG: sro:Sros_2812 hypothetical protein; SPTR: Putative uncharacterized protein. | SSU ribosomal protein S3P; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. | 0.980 |
| ADU48140.1 | ADU48121.1 | Intca_1627 | Intca_1608 | KEGG: cfl:Cfla_1864 protein of unknown function DUF2581; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2581). | KEGG: sro:Sros_2812 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.715 |
| ADU48140.1 | ADU48141.1 | Intca_1627 | Intca_1628 | KEGG: cfl:Cfla_1864 protein of unknown function DUF2581; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2581). | COGs: COG1853 Conserved protein/domain typically associated with flavoprotein oxygenase DIM6/NTAB family; InterPro IPR002563; KEGG: tcu:Tcur_3523 flavin reductase domain protein FMN-binding protein; PFAM: flavin reductase domain protein FMN-binding; SPTR: Nitrilotriacetate monooxygenase component B; PFAM: Flavin reductase like domain. | 0.788 |
| ADU48140.1 | ADU48258.1 | Intca_1627 | Intca_1745 | KEGG: cfl:Cfla_1864 protein of unknown function DUF2581; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2581). | KEGG: bfa:Bfae_16260 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.656 |
| ADU48140.1 | ADU48472.1 | Intca_1627 | Intca_1961 | KEGG: cfl:Cfla_1864 protein of unknown function DUF2581; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2581). | KEGG: kra:Krad_3230 hypothetical protein; SPTR: Putative transcriptional regulatory protein; TIGRFAM: DNA binding domain, excisionase family. | 0.688 |
| ADU48140.1 | ADU48546.1 | Intca_1627 | Intca_2035 | KEGG: cfl:Cfla_1864 protein of unknown function DUF2581; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2581). | KEGG: kse:Ksed_12170 hypothetical protein; SPTR: Methionine aminopeptidase. | 0.706 |
| ADU48140.1 | ADU50106.1 | Intca_1627 | Intca_3633 | KEGG: cfl:Cfla_1864 protein of unknown function DUF2581; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2581). | KEGG: ske:Sked_37910 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.670 |
| ADU48140.1 | hisE | Intca_1627 | Intca_1625 | KEGG: cfl:Cfla_1864 protein of unknown function DUF2581; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2581). | COGs: COG0140 Phosphoribosyl-ATP pyrophosphohydrolase; InterPro IPR008179: IPR021130; KEGG: nda:Ndas_5379 phosphoribosyl-ATP diphosphatase; PFAM: Phosphoribosyl-ATP pyrophosphohydrolase-like; SPTR: Phosphoribosyl-ATP diphosphatase; TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: Phosphoribosyl-ATP pyrophosphohydrolase; TIGRFAM: phosphoribosyl-ATP pyrophosphohydrolase. | 0.693 |
| ADU48140.1 | hisG | Intca_1627 | Intca_1626 | KEGG: cfl:Cfla_1864 protein of unknown function DUF2581; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2581). | ATP phosphoribosyltransferase (homohexameric); Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. | 0.828 |
| ADU48140.1 | ribH | Intca_1627 | Intca_1624 | KEGG: cfl:Cfla_1864 protein of unknown function DUF2581; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2581). | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.648 |
| ADU48140.1 | rpsC | Intca_1627 | Intca_2750 | KEGG: cfl:Cfla_1864 protein of unknown function DUF2581; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2581). | SSU ribosomal protein S3P; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. | 0.641 |
| ADU48141.1 | ADU48140.1 | Intca_1628 | Intca_1627 | COGs: COG1853 Conserved protein/domain typically associated with flavoprotein oxygenase DIM6/NTAB family; InterPro IPR002563; KEGG: tcu:Tcur_3523 flavin reductase domain protein FMN-binding protein; PFAM: flavin reductase domain protein FMN-binding; SPTR: Nitrilotriacetate monooxygenase component B; PFAM: Flavin reductase like domain. | KEGG: cfl:Cfla_1864 protein of unknown function DUF2581; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2581). | 0.788 |
| ADU48141.1 | hisE | Intca_1628 | Intca_1625 | COGs: COG1853 Conserved protein/domain typically associated with flavoprotein oxygenase DIM6/NTAB family; InterPro IPR002563; KEGG: tcu:Tcur_3523 flavin reductase domain protein FMN-binding protein; PFAM: flavin reductase domain protein FMN-binding; SPTR: Nitrilotriacetate monooxygenase component B; PFAM: Flavin reductase like domain. | COGs: COG0140 Phosphoribosyl-ATP pyrophosphohydrolase; InterPro IPR008179: IPR021130; KEGG: nda:Ndas_5379 phosphoribosyl-ATP diphosphatase; PFAM: Phosphoribosyl-ATP pyrophosphohydrolase-like; SPTR: Phosphoribosyl-ATP diphosphatase; TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: Phosphoribosyl-ATP pyrophosphohydrolase; TIGRFAM: phosphoribosyl-ATP pyrophosphohydrolase. | 0.602 |
| ADU48141.1 | hisG | Intca_1628 | Intca_1626 | COGs: COG1853 Conserved protein/domain typically associated with flavoprotein oxygenase DIM6/NTAB family; InterPro IPR002563; KEGG: tcu:Tcur_3523 flavin reductase domain protein FMN-binding protein; PFAM: flavin reductase domain protein FMN-binding; SPTR: Nitrilotriacetate monooxygenase component B; PFAM: Flavin reductase like domain. | ATP phosphoribosyltransferase (homohexameric); Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. | 0.778 |
| ADU48141.1 | ribH | Intca_1628 | Intca_1624 | COGs: COG1853 Conserved protein/domain typically associated with flavoprotein oxygenase DIM6/NTAB family; InterPro IPR002563; KEGG: tcu:Tcur_3523 flavin reductase domain protein FMN-binding protein; PFAM: flavin reductase domain protein FMN-binding; SPTR: Nitrilotriacetate monooxygenase component B; PFAM: Flavin reductase like domain. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.432 |
| ADU48258.1 | ADU48140.1 | Intca_1745 | Intca_1627 | KEGG: bfa:Bfae_16260 hypothetical protein; SPTR: Putative uncharacterized protein. | KEGG: cfl:Cfla_1864 protein of unknown function DUF2581; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2581). | 0.656 |
| ADU48258.1 | ADU48472.1 | Intca_1745 | Intca_1961 | KEGG: bfa:Bfae_16260 hypothetical protein; SPTR: Putative uncharacterized protein. | KEGG: kra:Krad_3230 hypothetical protein; SPTR: Putative transcriptional regulatory protein; TIGRFAM: DNA binding domain, excisionase family. | 0.633 |
| ADU48258.1 | ADU48546.1 | Intca_1745 | Intca_2035 | KEGG: bfa:Bfae_16260 hypothetical protein; SPTR: Putative uncharacterized protein. | KEGG: kse:Ksed_12170 hypothetical protein; SPTR: Methionine aminopeptidase. | 0.656 |