STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU48148.1ABC transporter related protein; COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterProIPR003593: IPR003439: IPR017940: IPR017871: IPR 001140; KEGG: tfu:Tfu_1158 ABC-type multidrug transport system ATPase and permease components; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; SPTR: ABC-type multidrug transport system ATPase and permease components; PFAM: ABC transporter transmembrane region; ABC transporter. (602 aa)    
Predicted Functional Partners:
ADU47993.1
ABC transporter related protein; COGs: COG1123 ATPase components of various ABC-type transport systems contain duplicated ATPase; InterPro IPR017871: IPR003439: IPR013563: IPR003593; KEGG: kfl:Kfla_4655 ABC transporter related protein; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; SPTR: ABC transporter related protein; PFAM: ABC transporter; Oligopeptide/dipeptide transporter, C-terminal region; Belongs to the ABC transporter superfamily.
     
0.865
ADU48147.1
ABC transporter related protein; COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterProIPR003593: IPR003439: IPR017940: IPR017871: IPR 001140; KEGG: tbi:Tbis_1444 ABC transporter-like protein; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; SPTR: ABC transporter related protein; PFAM: ABC transporter transmembrane region; ABC transporter.
 
    
0.827
ADU48146.1
GCN5-related N-acetyltransferase; COGs: COG3981 acetyltransferase; InterPro IPR000182; KEGG: kra:Krad_2568 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: Putative GCN5-related N-acetyltransferase; PFAM: Acetyltransferase (GNAT) family.
       0.773
ADU49927.1
Oligopeptide/dipeptide ABC transporter, ATPase subunit; COGs: COG1123 ATPase components of various ABC-type transport systems contain duplicated ATPase; InterProIPR003439: IPR013563: IPR010066: IPR017871: IPR 003593; KEGG: stp:Strop_3819 oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; SPTR: Oligopeptide/dipeptide ABC transporter, ATPase subunit; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter; Oligopeptide/dipeptide transporter, C-termi [...]
 
     
0.669
hisI
phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
       0.553
ADU48145.1
Hypothetical protein; InterPro IPR017517: IPR017519; KEGG: saq:Sare_3408 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Mycothiol maleylpyruvate isomerase N-terminal domain; TIGRFAM: conserved hypothetical protein TIGR03085; uncharacterized Actinobacterial protein TIGR03083.
       0.549
trpE
Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...]
  
  
 0.517
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.478
ADU47094.1
AAA ATPase central domain protein; COGs: COG0464 ATPase of the AAA+ class; InterPro IPR003959: IPR003593: IPR000641; KEGG: kfl:Kfla_5971 AAA ATPase central domain protein; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; SPTR: AAA ATPase central domain protein; PFAM: ATPase family associated with various cellular activities (AAA).
   
 0.451
ADU48151.1
InterPro IPR019051; KEGG: bcv:Bcav_2226 hypothetical protein; PFAM: Trp biosynthesis associated, transmembrane protein, Oprn/Chp; SPTR: Putative uncharacterized protein; PFAM: Tryptophan-associated transmembrane protein (Trp_oprn_chp).
       0.439
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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