STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU48151.1InterPro IPR019051; KEGG: bcv:Bcav_2226 hypothetical protein; PFAM: Trp biosynthesis associated, transmembrane protein, Oprn/Chp; SPTR: Putative uncharacterized protein; PFAM: Tryptophan-associated transmembrane protein (Trp_oprn_chp). (201 aa)    
Predicted Functional Partners:
trpE
Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...]
       0.837
ADU48152.1
KEGG: kfl:Kfla_3064 hypothetical protein; SPTR: Anthranilate synthase component I.
 
     0.726
hisI
phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
       0.720
ADU49559.1
Peptidase M12A astacin; InterPro IPR006026: IPR001506: IPR007280; KEGG: lch:Lcho_4313 peptidase domain-containing protein; PFAM: peptidase M12A astacin; peptidase domain protein; SMART: peptidase metallopeptidase; SPTR: Peptidase domain protein; PFAM: Astacin (Peptidase family M12A).
  
     0.710
ADU48157.1
Glutamate synthase (NADH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterProIPR017932: IPR000583: IPR006982: IPR002932: IPR 002489; KEGG: kfl:Kfla_3074 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Putative glutamate synthase (NADPH) large subunit; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
       0.679
ADU47587.1
KEGG: bcv:Bcav_3015 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.661
ADU48284.1
Hypothetical protein; KEGG: cai:Caci_1250 putative cellulose-binding protein; SPTR: Putative cellulose-binding protein.
  
     0.658
ADU47810.1
KEGG: kra:Krad_3784 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.648
lgt
Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.
 
     0.640
ADU47214.1
KEGG: kra:Krad_0632 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.619
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.