STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADU48195.1Protein of unknown function UPF0052 and CofD; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. (322 aa)    
Predicted Functional Partners:
ADU48194.1
Hypothetical protein; Displays ATPase and GTPase activities.
  
  
 0.962
whiA
Protein of unknown function DUF199; Involved in cell division and chromosome segregation.
 
  
 0.879
uvrC
Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
       0.828
ADU48192.1
Rieske (2Fe-2S) iron-sulfur domain; InterPro IPR017941: IPR006311; KEGG: sro:Sros_6043 ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenase-like protein; PFAM: Rieske [2Fe-2S] iron-sulphur domain; SPTR: Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenase-like protein; PFAM: Rieske [2Fe-2S] domain.
       0.614
uvrA
Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
       0.567
ADU48216.1
COGs: COG2345 transcriptional regulator protein; KEGG: kse:Ksed_13330 predicted transcriptional regulator; SPTR: Putative DNA-binding protein; PFAM: HTH domain.
  
     0.524
ADU48197.1
COGs: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; InterProIPR020832: IPR020830: IPR020831: IPR020828: IPR 020829: IPR006424; KEGG: kfl:Kfla_3261 glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; PRIAM: Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); SPTR: Glyceraldehyde-3-phosphate dehydrogenase, type I; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: Glyceraldehyde 3-phosphate dehydroge [...]
     
 0.514
ADU48188.1
Beta-lactamase domain-containing protein; COGs: COG0491 Zn-dependent hydrolase including glyoxylase; KEGG: saq:Sare_3342 beta-lactamase domain-containing protein; SPTR: Putative Zn-dependent hydrolase; PFAM: Metallo-beta-lactamase superfamily.
     
 0.495
ADU48749.1
GCN5-related N-acetyltransferase; COGs: COG3393 acetyltransferase; InterPro IPR016794: IPR000182; KEGG: kse:Ksed_11380 predicted acyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: Putative acetyltransferase; PFAM: Acetyltransferase (GNAT) family.
  
     0.486
glmU
Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.
 
   
 0.453
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.