Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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Score
ADU48210.1Cytochrome oxidase assembly; COGs: COG1612 Uncharacterized protein required for cytochrome oxidase assembly; InterPro IPR003780; KEGG: kse:Ksed_13300 uncharacterized protein required for cytochrome oxidase assembly; PFAM: cytochrome oxidase assembly; SPTR: Putative cytochrome c oxidase subunit XV assembly protein; PFAM: Cytochrome oxidase assembly protein. (327 aa)    
Predicted Functional Partners:
ctaB
Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
 
 0.994
ADU49474.1
Hypothetical protein; KEGG: pac:PPA0649 putative cytochrome oxidase assembly protein; SPTR: Putative cytochrome oxidase assembly protein; PFAM: Cytochrome oxidase assembly protein.
  
  
  0.912
ADU48496.1
COGs: COG1290 Cytochrome b subunit of the bc complex; InterPro IPR005797; KEGG: kse:Ksed_16210 cytochrome b subunit of the bc complex; PFAM: Cytochrome b/b6 domain; SPTR: Cytochrome B subunit; PFAM: Cytochrome b(N-terminal)/b6/petB.
 
  
 0.856
ADU48231.1
COGs: COG3346 conserved hypothetical protein; InterPro IPR002994; KEGG: kse:Ksed_13470 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: SURF1 family.
 
 0.854
ADU47556.1
COGs: COG3346 conserved hypothetical protein; InterPro IPR002994; KEGG: kse:Ksed_07660 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: SURF1 family.
 
 0.828
ADU48494.1
Menaquinol-cytochrome c reductase cytochrome c1 subunit precursor; InterPro IPR003088: IPR009152: IPR009056; KEGG: kse:Ksed_16190 cytochrome c, mono- and diheme variants family; PFAM: cytochrome c class I; SPTR: Cytochrome C heme-binding subunit; PFAM: Cytochrome c.
 
  
 0.756
ADU48212.1
ABC-2 type transporter; InterPro IPR013525; KEGG: kse:Ksed_13310 ABC-type multidrug transport system, permease component; PFAM: ABC-2 type transporter; SPTR: ABC-type multidrug transport system, permease component; PFAM: ABC-2 type transporter; TIGRFAM: ABC transporter efflux protein, DrrB family.
 
     0.721
ADU48499.1
Cytochrome c oxidase, subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
 
 
 0.720
ADU48500.1
COGs: COG1622 Heme/copper-type cytochrome/quinol oxidase subunit 2; InterPro IPR002429: IPR014222: IPR001505; KEGG: cfl:Cfla_2082 cytochrome c oxidase, subunit II; PFAM: cytochrome c oxidase subunit II; SPTR: Cytochrome c oxidase subunit 2; TIGRFAM: cytochrome c oxidase, subunit II; PFAM: Cytochrome C oxidase subunit II, periplasmic domain; TIGRFAM: cytochrome c oxidase, subunit II.
 
 
 0.715
ADU48209.1
NUDIX hydrolase; COGs: COG1670 Acetyltransferase including N-acetylase of ribosomal protein; InterPro IPR000182: IPR020476: IPR020084: IPR000086; KEGG: kfl:Kfla_4957 NUDIX hydrolase; PFAM: NUDIX hydrolase; GCN5-related N-acetyltransferase; SPTR: NUDIX hydrolase; PFAM: Acetyltransferase (GNAT) family; NUDIX domain; Belongs to the Nudix hydrolase family.
 
     0.704
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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