Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADU48229.1ABC transporter related protein; COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterProIPR003593: IPR003439: IPR017940: IPR017871: IPR 001140; KEGG: kfl:Kfla_3305 ABC transporter related protein; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; SPTR: ABC-type multidrug transport system ATPase and permease component; PFAM: ABC transporter transmembrane region; ABC transporter. (638 aa)    
Predicted Functional Partners:
ADU49927.1
Oligopeptide/dipeptide ABC transporter, ATPase subunit; COGs: COG1123 ATPase components of various ABC-type transport systems contain duplicated ATPase; InterProIPR003439: IPR013563: IPR010066: IPR017871: IPR 003593; KEGG: stp:Strop_3819 oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; SPTR: Oligopeptide/dipeptide ABC transporter, ATPase subunit; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter; Oligopeptide/dipeptide transporter, C-termi [...]
 
     
0.890
pstB
Phosphate ABC transporter ATP-binding protein, PhoT family; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
 
     
0.883
ADU48230.1
KEGG: sna:Snas_5699 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF664).
       0.594
ADU46838.1
ABC transporter related protein; COGs: COG1125 ABC-type proline/glycine betaine transport systems ATPase components; InterPro IPR003439: IPR003593: IPR017871; KEGG: kse:Ksed_26260 glycine betaine/L-proline transport ATP binding subunit; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Putative ABC transporter ATP-binding subunit; PFAM: ABC transporter; TIGRFAM: glycine betaine/L-proline transport ATP binding subunit.
 
     
0.590
arc
AAA ATPase central domain protein; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
  
 
  0.522
ADU47191.1
COGs: COG0123 Deacetylase including yeast histone deacetylase and acetoin utilization protein; InterPro IPR000286; KEGG: kra:Krad_0611 histone deacetylase superfamily; PFAM: histone deacetylase superfamily; PRIAM: Histone deacetylase; SPTR: Putative acetoin utilization protein; PFAM: Histone deacetylase domain.
  
 0.498
ADU48228.1
KEGG: ami:Amir_1238 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.486
ADU48227.1
COGs: COG0488 ATPase components of ABC transporter with duplicated ATPase domains; InterPro IPR003593: IPR003439: IPR017871; KEGG: kse:Ksed_13460 ATPase component of ABC transporters with duplicated ATPase domain; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Putative ABC transporter ATP binding protein; PFAM: ABC transporter.
 
 
0.480
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.471
ADU48099.1
Oligopeptide/dipeptide ABC transporter, ATPase subunit; COGs: COG1123 ATPase components of various ABC-type transport systems contain duplicated ATPase; InterProIPR003593: IPR003439: IPR017871: IPR013563: IPR 010066; KEGG: kse:Ksed_12500 oligopeptide/dipeptide ABC transporter, ATP-binding protein; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; SPTR: Oligopeptide/dipeptide ABC transporter, ATP-binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter; Oligopeptide/dipeptide transporte [...]
     
0.448
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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