Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADU48249.1tRNA/rRNA methyltransferase (SpoU); COGs: COG0566 rRNA methylase; InterPro IPR001537; KEGG: kse:Ksed_13580 rRNA methylase; PFAM: tRNA/rRNA methyltransferase (SpoU); SPTR: RRNA methyltransferase; PFAM: SpoU rRNA Methylase family. (271 aa)    
Predicted Functional Partners:
ADU48247.1
Protein of unknown function DUF81; InterPro IPR002781; KEGG: nfa:nfa3090 hypothetical protein; PFAM: protein of unknown function DUF81; SPTR: Putative uncharacterized protein; PFAM: Sulfite exporter TauE/SafE.
       0.787
ADU48248.1
Protein of unknown function DUF81; InterPro IPR002781; KEGG: tfu:Tfu_1919 hypothetical protein; PFAM: protein of unknown function DUF81; SPTR: Putative uncharacterized protein; PFAM: Sulfite exporter TauE/SafE.
       0.745
ADU48246.1
SPFH domain, Band 7 family protein; COGs: COG0330 Membrane protease subunits stomatin/prohibitin homologs; InterPro IPR001107: IPR001972: IPR018080; KEGG: bcv:Bcav_2313 band 7 protein; PFAM: band 7 protein; SMART: band 7 protein; SPTR: Putative secreted protein; PFAM: SPFH domain / Band 7 family.
  
   0.653
pheT
COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; InterProIPR002547: IPR005121: IPR004532: IPR005146: IPR 005147; KEGG: kra:Krad_3163 phenylalanyl-tRNA synthetase, beta subunit; PFAM: B3/4 domain protein; t-RNA-binding domain-containing protein; tRNA synthetase B5; ferredoxin-fold anticodon-binding; SPTR: Phenylalanyl-tRNA synthetase beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; PFAM: tRNA synthetase B5 domain; Ferredoxin-fold anticodon binding domain; B3/4 domain; Putative tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit, non-spiroch [...]
  
  
 0.532
ADU48245.1
Protein of unknown function DUF107; COGs: COG1585 Membrane protein implicated in regulation of membrane protease activity; InterPro IPR002810; KEGG: kra:Krad_3088 protein of unknown function DUF107; PFAM: protein of unknown function DUF107; SPTR: Putative integral membrane protein; PFAM: NfeD-like.
       0.531
ADU48556.1
COGs: COG0557 Exoribonuclease R; InterPro IPR001900; KEGG: kse:Ksed_12120 exoribonuclease R; PFAM: ribonuclease II; SPTR: Putative ribonuclease R; PFAM: RNB domain.
  
 
 0.531
rplU
LSU ribosomal protein L21P; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
   
 
 0.517
ADU48244.1
ABC transporter related protein; COGs: COG1119 ABC-type molybdenum transport system ATPase component/photorepair protein PhrA; InterPro IPR003593: IPR003439; KEGG: kse:Ksed_13560 ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA; PFAM: ABC transporter.
     
 0.507
rplC
LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
   
 
 0.469
rplM
LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
 
 0.467
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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