STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
nnrDCarbohydrate kinase, YjeF related protein; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. (311 aa)    
Predicted Functional Partners:
ADU48253.1
Phosphoglycerate mutase; COGs: COG0406 Fructose-2 6-bisphosphatase; InterPro IPR013078; KEGG: kra:Krad_3699 phosphoglycerate mutase; PFAM: Phosphoglycerate mutase; SPTR: Phosphoglycerate mutase; PFAM: Phosphoglycerate mutase family.
 
    0.921
ADU48250.1
KEGG: nca:Noca_2347 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3037).
 
     0.597
ADU48252.1
InterPro IPR011701; KEGG: kfl:Kfla_7034 major facilitator superfamily MFS_1; PFAM: major facilitator superfamily MFS_1; SPTR: Major facilitator superfamily MFS_1; PFAM: Major Facilitator Superfamily.
       0.546
ADU48251.1
KEGG: kse:Ksed_13600 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.545
ADU50029.1
KEGG: pfr:PFREUD_00910 hypothetical membrane protein; SPTR: Hypothetical membrane protein; PFAM: Protein of unknown function (DUF3618).
  
     0.500
nnrE
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
 
  
0.491
ADU50027.1
KEGG: aau:AAur_0122 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.480
ADU48255.1
Peptidase M20; COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR001261: IPR002933: IPR011650; KEGG: bcv:Bcav_2253 hypothetical protein; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: Putative uncharacterized protein; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain.
       0.428
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.