STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mshCcysteinyl-tRNA synthetase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily. (418 aa)    
Predicted Functional Partners:
mshD
Mycothiol biosynthesis acetyltransferase; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
 
  
 0.866
ADU48265.1
KEGG: sen:SACE_2204 phosphatidylinositol 3-and 4-kinase, catalytic; SPTR: Phosphatidylinositol 3-and 4-kinase, catalytic; PFAM: Phosphatidylinositol 3- and 4-kinase; TIGRFAM: conserved hypothetical protein.
 
     0.837
mca
Mycothiol conjugate amidase Mca; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S- conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics; Belongs to the MshB deacetylase family. Mca subfamily.
 
  
 0.829
ADU48264.1
KEGG: kra:Krad_1834 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3090); TIGRFAM: conserved hypothetical protein.
 
     0.824
ADU48263.1
Phosphoglycerate mutase; COGs: COG0406 Fructose-2 6-bisphosphatase; InterPro IPR013078; KEGG: kra:Krad_1833 phosphoglycerate mutase; PFAM: Phosphoglycerate mutase; SPTR: Phosphoglycerate mutase; PFAM: Phosphoglycerate mutase family; TIGRFAM: probable phosphomutase, MSMEG_4193 family.
 
     0.794
ADU49116.1
1D-myo-inosityl-2-acetamido-2-deoxy-alpha-D-gluc opyranosidedeacetylase; COGs: COG2120 conserved hypothetical protein LmbE homologs; InterPro IPR017810: IPR003737; KEGG: sma:SAV_3138 N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D- glucopyranoside deacetylase; PFAM: LmbE family protein; SPTR: Putative N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D- glucopyranoside deacetylase; TIGRFAM:1D-myo-inosityl-2-acetamido-2-deoxy-alpha-D -glucopyranosidedeacetylase; PFAM: GlcNAc-PI de-N-acetylase; TIGRFAM: 1D-myo-inosityl-2-acetamido-2-deoxy-alpha-D- glucopyranoside deacetylase; Belongs to [...]
 
 
 0.758
ADU46859.1
COGs: COG1045 Serine acetyltransferase; InterPro IPR001451: IPR005881: IPR018357; KEGG: bfa:Bfae_12330 serine O-acetyltransferase; SPTR: Serine acetyltransferase; TIGRFAM: serine O-acetyltransferase; TIGRFAM: serine O-acetyltransferase.
 
  
 0.738
pheT
COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; InterProIPR002547: IPR005121: IPR004532: IPR005146: IPR 005147; KEGG: kra:Krad_3163 phenylalanyl-tRNA synthetase, beta subunit; PFAM: B3/4 domain protein; t-RNA-binding domain-containing protein; tRNA synthetase B5; ferredoxin-fold anticodon-binding; SPTR: Phenylalanyl-tRNA synthetase beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; PFAM: tRNA synthetase B5 domain; Ferredoxin-fold anticodon binding domain; B3/4 domain; Putative tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit, non-spiroch [...]
  
  
 0.707
ADU47878.1
KEGG: jde:Jden_0944 hypothetical protein; SPTR: Putative uncharacterized protein; manually curated; PFAM: DSBA-like thioredoxin domain.
  
  
 0.694
ADU47778.1
Transferase hexapeptide repeat containing protein; COGs: COG1045 Serine acetyltransferase; InterPro IPR018357: IPR001451; KEGG: gur:Gura_1700 serine acetyltransferase-like protein; PFAM: transferase hexapeptide repeat containing protein; SPTR: Pilin glycosylation protein; TIGRFAM: sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family.
  
  
 0.660
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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