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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU48273.1COGs: COG2887 RecB family exonuclease; KEGG: kfl:Kfla_3207 RecB family exonuclease-like protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2800). (279 aa)    
Predicted Functional Partners:
ADU48274.1
Peptidase M50; COGs: COG1994 Zn-dependent protease; InterPro IPR000644: IPR008915; KEGG: xce:Xcel_1483 peptidase M50; PFAM: peptidase M50; SPTR: Putative peptidase; PFAM: Peptidase family M50.
 
    0.649
ADU48374.1
Hypothetical protein; InterPro IPR016160; KEGG: kra:Krad_3061 hypothetical protein; SPTR: Putative secreted protein.
  
     0.580
ADU48376.1
COGs: COG1560 Lauroyl/myristoyl acyltransferase; InterPro IPR004960; KEGG: kra:Krad_3063 lipid A biosynthesis lauroyl acyltransferase; PFAM: lipid A biosynthesis acyltransferase; SPTR: Lipid A biosynthesis lauroyl acyltransferase; PFAM: Bacterial lipid A biosynthesis acyltransferase.
  
     0.576
ADU48375.1
Phosphatidylinositol alpha-mannosyltransferase; COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: xce:Xcel_1660 glycosyl transferase group 1; PFAM: glycosyl transferase group 1; PRIAM: Phosphatidylinositol alpha-mannosyltransferase; SPTR: Putative glycosyltransferase; PFAM: Glycosyl transferases group 1.
  
     0.561
whiB-3
Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
     0.524
ADU48276.1
COGs: COG2519 tRNA(1-methyladenosine) methyltransferase and related methyltransferase; InterPro IPR014816; KEGG: cfl:Cfla_2005 tRNA (adenine-N(1)-)-methyltransferase; PFAM: tRNA methyltransferase complex GCD14 subunit; PRIAM: tRNA (adenine-N(1)-)-methyltransferase; SPTR: Putative uncharacterized protein; PFAM: tRNA methyltransferase complex GCD14 subunit.
 
     0.504
pup
Protein of unknown function DUF797; Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
 
     0.446
ADU50095.1
Transcriptional regulator, PadR family; COGs: COG1695 transcriptional regulator protein; InterPro IPR005149; KEGG: ace:Acel_2137 PadR family transcriptional regulator; PFAM: transcriptional regulator PadR family protein; SPTR: Transcriptional regulator, PadR family; PFAM: Transcriptional regulator PadR-like family.
  
     0.441
arc
AAA ATPase central domain protein; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
 
     0.440
ADU48275.1
InterPro IPR000424; KEGG: nca:Noca_2477 single-strand binding protein/primosomal replication protein N; PFAM: single-strand binding protein/Primosomal replication protein n; SPTR: Putative uncharacterized protein; PFAM: Single-strand binding protein family.
 
     0.435
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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