Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADU48275.1InterPro IPR000424; KEGG: nca:Noca_2477 single-strand binding protein/primosomal replication protein N; PFAM: single-strand binding protein/Primosomal replication protein n; SPTR: Putative uncharacterized protein; PFAM: Single-strand binding protein family. (140 aa)    
Predicted Functional Partners:
ADU47855.1
COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR011344: IPR000424; KEGG: fra:Francci3_1145 single-stranded DNA-binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; SPTR: Single-stranded DNA-binding protein; TIGRFAM: single-strand binding protein; PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb).
     
  0.900
ADU50089.1
COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR000424: IPR011344; KEGG: kra:Krad_4338 single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; SPTR: Single-stranded DNA-binding protein; TIGRFAM: single-strand binding protein; PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb).
     
  0.900
rpsF
SSU ribosomal protein S6P; Binds together with S18 to 16S ribosomal RNA.
  
  
 0.793
ADU48276.1
COGs: COG2519 tRNA(1-methyladenosine) methyltransferase and related methyltransferase; InterPro IPR014816; KEGG: cfl:Cfla_2005 tRNA (adenine-N(1)-)-methyltransferase; PFAM: tRNA methyltransferase complex GCD14 subunit; PRIAM: tRNA (adenine-N(1)-)-methyltransferase; SPTR: Putative uncharacterized protein; PFAM: tRNA methyltransferase complex GCD14 subunit.
   
   0.771
priA
Primosomal protein N' (replication factor Y) - superfamily II helicase-like protein; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.
   
 
 0.769
ADU48045.1
COGs: COG0587 DNA polymerase III alpha subunit; InterProIPR004805: IPR004013: IPR011708: IPR004365: IPR 003141; KEGG: kse:Ksed_16450 DNA polymerase III subunit alpha; PFAM: DNA polymerase III alpha subunit; PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; PRIAM: DNA-directed DNA polymerase; SMART: phosphoesterase PHP domain protein; SPTR: DNA polymerase III subunit alpha; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: Bacterial DNA polymerase III alpha subunit; PHP domain; OB-fold nucleic acid binding domain; TIGRFAM: DNA-directed DNA polymerase III (polc).
   
 
 0.740
ADU48466.1
COGs: COG0587 DNA polymerase III alpha subunit; InterProIPR004013: IPR011708: IPR004365: IPR003141: IPR 004805; KEGG: kra:Krad_3215 DNA polymerase III, alpha subunit; PFAM: DNA polymerase III alpha subunit; PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; PRIAM: DNA-directed DNA polymerase; SMART: phosphoesterase PHP domain protein; SPTR: Putative DNA polymerase III alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: PHP domain; Bacterial DNA polymerase III alpha subunit; OB-fold nucleic acid binding domain; TIGRFAM: DNA-directed DNA polymerase III (pol [...]
   
 
 0.740
dnaX
DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
    
 
 0.736
ADU47116.1
COGs: COG2812 DNA polymerase III gamma/tau subunits; InterPro IPR003593; KEGG: kse:Ksed_24860 DNA polymerase III, gamma/tau subunit; SMART: AAA ATPase; SPTR: ATPase; PFAM: ATPase family associated with various cellular activities (AAA); TIGRFAM: DNA polymerase III, delta' subunit.
    
 
 0.736
rpsB
COGs: COG0052 Ribosomal protein S2; InterPro IPR005706: IPR018130: IPR001865; KEGG: xce:Xcel_1180 ribosomal protein S2; PFAM: ribosomal protein S2; SPTR: 30S ribosomal protein S2; TIGRFAM: ribosomal protein S2; PFAM: Ribosomal protein S2; TIGRFAM: ribosomal protein S2, bacterial type; Belongs to the universal ribosomal protein uS2 family.
   
  0.669
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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