STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADU48287.1COGs: COG0545 FKBP-type peptidyl-prolyl cis-trans isomerase 1; InterPro IPR001179; KEGG: kse:Ksed_13970 FKBP-type peptidyl-prolyl cis-trans isomerase; PFAM: peptidylprolyl isomerase FKBP-type; SPTR: FKBP-type peptidyl-prolyl cis-trans isomerase; PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase. (342 aa)    
Predicted Functional Partners:
infA
Bacterial translation initiation factor 1 (bIF-1); One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
   
   0.763
ADU46982.1
COGs: COG0527 Aspartokinase; InterProIPR001048: IPR002912: IPR018042: IPR005260: IPR 001341; KEGG: tcu:Tcur_4886 aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; SPTR: Aspartokinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: Amino acid kinase family; ACT domain; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase; Belongs to the aspartokinase family.
    
   0.725
ADU48288.1
Peptidylprolyl isomerase; COGs: COG0545 FKBP-type peptidyl-prolyl cis-trans isomerase 1; InterPro IPR001179; KEGG: kse:Ksed_13980 FKBP-type peptidyl-prolyl cis-trans isomerase; PFAM: peptidylprolyl isomerase FKBP-type; PRIAM: Peptidylprolyl isomerase; SPTR: Peptidyl-prolyl cis-trans isomerase; PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase.
 
    
0.721
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 0.651
pafA
Protein of unknown function DUF245 domain protein; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine.
       0.623
ADU48130.1
Fmu (Sun) domain protein; COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR006027: IPR001678; KEGG: cfl:Cfla_1856 Fmu (Sun) domain protein; PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; SPTR: Putative RNA-binding Sun protein; PFAM: NOL1/NOP2/sun family; NusB family; TIGRFAM: ribosomal RNA small subunit methyltransferase RsmB; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
 
   0.580
ADU48391.1
InterPro IPR001440: IPR019734: IPR013026; KEGG: cyp:PCC8801_1300 TPR repeat-containing protein; PFAM: Tetratricopeptide TPR_1 repeat-containing protein; SMART: Tetratricopeptide repeat; SPTR: TPR repeat-containing protein; PFAM: Tetratricopeptide repeat.
  
 
 0.525
ADU48076.1
KEGG: sen:SACE_5253 hypothetical protein; SPTR: Putative uncharacterized protein; manually curated.
  
 
 0.517
ADU48011.1
COGs: COG1643 HrpA-like helicase; InterProIPR010222: IPR001650: IPR007502: IPR011709: IPR 014001: IPR003593: IPR014021; KEGG: stp:Strop_1712 ATP-dependent helicase HrpA; PFAM: protein of unknown function DUF1605; helicase-associated domain protein; helicase domain protein; SMART: DEAD-like helicase; AAA ATPase; helicase domain protein; SPTR: ATP-dependent helicase HrpA; TIGRFAM: ATP-dependent helicase HrpA; manually curated; PFAM: Helicase conserved C-terminal domain; Helicase associated domain (HA2); Domain of unknown function (DUF3418); Domain of unknown function (DUF1605); DEAD/DEAH [...]
 
 0.501
ADU48420.1
COGs: COG0728 membrane protein putative virulence factor; InterPro IPR004268; KEGG: kse:Ksed_26920 integral membrane protein MviN; PFAM: virulence factor MVIN family protein; SPTR: Integral membrane protein MviN; TIGRFAM: integral membrane protein MviN; PFAM: MviN-like protein; TIGRFAM: integral membrane protein MviN.
  
   
 0.497
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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