STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tatATwin-arginine translocation protein, TatA/E family subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. (111 aa)    
Predicted Functional Partners:
tatC
Sec-independent protein translocase, TatC subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
  
 0.990
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
  
 0.925
ADU49097.1
Twin-arginine translocation protein, TatB subunit; InterPro IPR018448: IPR003998; KEGG: rsa:RSal33209_1193 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: twin-arginine translocation protein, TatB subunit; PFAM: mttA/Hcf106 family; TIGRFAM: twin arginine-targeting protein translocase TatB.
     
 0.686
ADU46620.1
Rhomboid family protein; COGs: COG0705 membrane protein; InterPro IPR002610; KEGG: xce:Xcel_0012 rhomboid family protein; PFAM: Rhomboid family protein; SPTR: Rhomboid family protein; PFAM: Rhomboid family.
   
 
 0.666
secA
Protein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
      
 0.666
ADU48295.1
DEAD/DEAH box helicase domain protein; COGs: COG4581 Superfamily II RNA helicase; InterProIPR014001: IPR001650: IPR014021: IPR011545: IPR 012961; KEGG: sgr:SGR_5873 putative ATP-dependent RNA helicase; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; DSH domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: Putative ATP-dependent RNA helicase; PFAM: Helicase conserved C-terminal domain; DSHCT (NUC185) domain; DEAD/DEAH box helicase.
       0.657
secY
Protein translocase subunit secY/sec61 alpha; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
      
 0.650
ftsY
Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
   
  
 0.649
ADU48290.1
COGs: COG2378 transcriptional regulator protein; KEGG: kra:Krad_1879 transcriptional regulator-like; SPTR: Transcriptional regulator-like protein.
 
  
 0.621
secD
Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
 
  
 0.580
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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