STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU48295.1DEAD/DEAH box helicase domain protein; COGs: COG4581 Superfamily II RNA helicase; InterProIPR014001: IPR001650: IPR014021: IPR011545: IPR 012961; KEGG: sgr:SGR_5873 putative ATP-dependent RNA helicase; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; DSH domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: Putative ATP-dependent RNA helicase; PFAM: Helicase conserved C-terminal domain; DSHCT (NUC185) domain; DEAD/DEAH box helicase. (959 aa)    
Predicted Functional Partners:
tatC
Sec-independent protein translocase, TatC subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
       0.825
ADU48294.1
Diacylglycerol kinase catalytic region; COGs: COG1597 Sphingosine kinase; InterPro IPR001206: IPR005218; KEGG: sro:Sros_5857 hypothetical protein; PFAM: diacylglycerol kinase catalytic region; SMART: diacylglycerol kinase catalytic region; SPTR: Putative uncharacterized protein; PFAM: Diacylglycerol kinase catalytic domain; TIGRFAM: lipid kinase, YegS/Rv2252/BmrU family.
       0.798
tatA
Twin-arginine translocation protein, TatA/E family subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
       0.657
rbpA-2
Hypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
 
    0.634
ADU48290.1
COGs: COG2378 transcriptional regulator protein; KEGG: kra:Krad_1879 transcriptional regulator-like; SPTR: Transcriptional regulator-like protein.
 
     0.617
ADU48200.1
Protein translocase subunit secG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
  
     0.593
ADU49118.1
GTP-binding protein TypA; COGs: COG1217 membrane GTPase involved in stress response; InterProIPR005225: IPR006298: IPR000795: IPR004161: IPR 000640; KEGG: sro:Sros_7974 GTP-binding protein TypA; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain-containing protein; SPTR: Small GTP-binding protein domain:GTP-binding protein TypA; TIGRFAM: GTP-binding protein TypA; small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; TIGRFAM: GTP-binding protein T [...]
      
 0.583
whiB-4
Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
     0.553
ADU48328.1
Regulatory protein MerR; InterPro IPR000551; KEGG: aau:AAur_1684 hypothetical protein; SMART: regulatory protein MerR; SPTR: Putative uncharacterized protein.
  
     0.544
ADU48291.1
Hypothetical protein; COGs: COG2378 transcriptional regulator protein; KEGG: kra:Krad_1880 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.533
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.