STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
ADU48315.123S rRNA m(5)U-747 methyltransferase; COGs: COG2265 SAM-dependent methyltransferase related to tRNA (uracil-5-)-methyltransferase; InterPro IPR010280; KEGG: ach:Achl_1142 23S rRNA methyluridine methyltransferase; PFAM: (Uracil-5)-methyltransferase; SPTR: 23S rRNA (Uracil-5-)-methyltransferase RumB; PFAM: tRNA (Uracil-5-)-methyltransferase; TIGRFAM: 23S rRNA (uracil-5-)-methyltransferase RumB; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (394 aa)    
Predicted Functional Partners:
ADU48316.1
Protein of unknown function UCP012608; COGs: COG4427 conserved hypothetical protein; InterPro IPR000276: IPR011200; KEGG: amd:AMED_1098 hypothetical protein; PFAM: protein of unknown function UCP012608; SPTR: Uncharacterized conserved protein; PFAM: Uncharacterized protein conserved in bacteria (DUF2332).
       0.777
ADU48276.1
COGs: COG2519 tRNA(1-methyladenosine) methyltransferase and related methyltransferase; InterPro IPR014816; KEGG: cfl:Cfla_2005 tRNA (adenine-N(1)-)-methyltransferase; PFAM: tRNA methyltransferase complex GCD14 subunit; PRIAM: tRNA (adenine-N(1)-)-methyltransferase; SPTR: Putative uncharacterized protein; PFAM: tRNA methyltransferase complex GCD14 subunit.
   
  
 0.527
ADU48314.1
KEGG: cwo:Cwoe_5391 hypothetical protein; SPTR: Putative transcriptional regulator.
       0.508
ADU48130.1
Fmu (Sun) domain protein; COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR006027: IPR001678; KEGG: cfl:Cfla_1856 Fmu (Sun) domain protein; PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; SPTR: Putative RNA-binding Sun protein; PFAM: NOL1/NOP2/sun family; NusB family; TIGRFAM: ribosomal RNA small subunit methyltransferase RsmB; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
 
  
 0.477
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
  
 0.469
trmB
tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
  
  
 0.457
ADU47001.1
ABC transporter related protein; COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR003439: IPR017940: IPR003593; KEGG: nca:Noca_2806 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter transmembrane region; ABC transporter.
 
     0.434
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.